Results 261 to 270 of about 401,649 (316)
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HLA and longevity

Tissue Antigens, 1982
One hundred fifty‐five healthy nonagenarians, 55 men and 100 women, all French Caucasians, were phenotyped for alleles of the A, B, C, DR loci of the HLA complex. The observed HLA antigen frequencies were compared to those of a control series of 133 males and 179 females whose ages ranged from 10 to 50 years.
J, Proust   +6 more
openaire   +2 more sources

HLA and disease

European Journal of Epidemiology, 2005
Association of HLA and diseases is well known. Several population studies are available suggesting evidence of association of HLAs in more than 40 diseases. HLA found across various populations vary widely. Some of the reasons attributed for such variation are occurrence of social stratification based on geography, language and religion, consequences ...
Yogita, Ghodke   +3 more
openaire   +2 more sources

Association of HLA-Ib (HLA-G, HLA-E and HLA-F) with spontaneous HBV clearance

Infectious Diseases
The natural history of HBV infection is highly heterogeneous. Failure to clear the virus during the acute phase of infection allows for viral persistence and progression to chronicity. Investigating the immune mechanisms involved in this process is crucial for effectively managing infection outcome.
Ahmed Baligh, Laaribi   +6 more
openaire   +2 more sources

HLA and Disease

CRC Critical Reviews in Clinical Laboratory Sciences, 1984
This review describes the greater portion of a large number of new studies on HLA and disease association which has appeared in the literature since 1979. The majority of these are concerned with the association of certain diseases with class II major histocompatibility complex antigens. The possible biologic significance of these associations in terms
Chester M. Zmijewski, Thomas C. Fuller
openaire   +2 more sources

HLA in transplantation

Nature Reviews Nephrology, 2018
The human major histocompatibility complex is a family of genes that encodes HLAs, which have a crucial role in defence against foreign pathogens and immune surveillance of tumours. In the context of transplantation, HLA molecules are polymorphic antigens that comprise an immunodominant alloreactive trigger for the immune response, resulting in ...
Robert A, Montgomery   +3 more
openaire   +2 more sources

HLA and autism

Journal of Autism and Developmental Disorders, 1980
The authors, along with other investigators, postulate that viruses may be one of the causes of the syndrome of autism. Many diseases, especially those where a viral infection and autoimmunity is suspected, are being studied to determine whether an association with histocompatibility antigens (human leukocyte antigens--HLA) exists.
E G, Stubbs, R E, Magenis
openaire   +2 more sources

A roadmap for HLA-A, HLA-B, and HLA-C peptide binding specificities

Immunogenetics, 1996
The high level of polymorphism in major histocompatibility complex (MHC) molecules leads to many allele-specific peptide binding repertoires that can generally be characterized by sequence motifs. Such motifs have previously been elucidated experimentally for several MHC molecules and shown to bind in specificity pockets in the antigen binding cleft ...
openaire   +2 more sources

HLA and Glioma

Tissue Antigens, 1978
HLA typing of 80 glioma patients was determined and the antigen frequencies were compared with 176 normal controls. Increased phenotypic frequencies of Bw35 and DRw1 were observed, but when P values were corrected by the number of antigens tested (35), the results were no longer significant.
P, de Moerloose   +5 more
openaire   +2 more sources

HLA and syringomyelia

Journal of Neuroimmunology, 1982
The HLA status of 53 patients with syringomyelia was assessed. Forty had an associated Chiari anomaly. A significant increase of HLA-A9 was found. Genetic factors may influence the development of syringomyelia.
P K, Newman, J, Wentzel, J B, Foster
openaire   +2 more sources

HLA and keratoconus

Tissue Antigens, 1983
HLA‐A and ‐B antigens were determined in 64 Caucasoid patients with keratoconus. A highly significant increase in the frequency of HLA‐B5 was found among the patients. Thus keratoconus is the third eye disease after recurrent herpetic keratitis and Behcet's disease showing an association with HLA‐B5.
P T, Klouda   +5 more
openaire   +2 more sources

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