Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang +14 more
wiley +1 more source
Baseline Dynamics and Sleep Loss-Driven Changes of Electrocorticographic Aperiodic Properties Are Altered in Mice Lacking Neuroligin-2. [PDF]
Leduc T +5 more
europepmc +1 more source
Additive Manufacturing of High‐Performance Polymers for Extreme Environments
Additive manufacturing of high‐performance polymers for extreme environments is critically reviewed through an integrated chemistry‐processing‐structure‐property‐qualification framework. The review compares fused filament fabrication, selective laser sintering, and direct ink writing, linking rheology and thermal history to crystallization, defect ...
Md Tofazzal Hossain +7 more
wiley +1 more source
MRI-guided microwave ablation of hepatic malignancies: 4-year institutional outcomes. [PDF]
Düx DM +7 more
europepmc +1 more source
A zwitterionic copolymer, Poly(2‐methacryloyloxyethyl phosphorylcholine‐co‐2‐aminoethyl methacrylate hydrochloride) (P(MPC‐co‐AEMA)) copolymers, with tunable MPC/AEMA ratios, is grafted onto the polyamide (PA) selective layer via secondary interfacial polymerization. Balancing reactive anchoring segments (AEMA) and zwitterionic segments (MPC) regulated
Shaofan Duan +13 more
wiley +1 more source
Manganese Transport and Sediment Remobilization in a Tidal Estuary: Parameter Sensitivity and Uncertainty Analysis. [PDF]
Liu HM, Liu WC, Huang WC, Young CC.
europepmc +1 more source
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang +7 more
wiley +1 more source
Integrated Protein-Lipid Digestion Profiles of Human Milk, Infant Formulas, and Dairy Ingredients Under Infant In Vitro Digestion. [PDF]
Chen B +11 more
europepmc +1 more source
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou +11 more
wiley +1 more source
High-performance eco-engineered uranyl nanocomposite based on Schiff base-modified nanocellulose: from DFT insight to real-water analysis. [PDF]
Alessa H +9 more
europepmc +1 more source

