Results 41 to 50 of about 324,876 (288)

Public Interest Immunity: Al Megrahi v HM Advocate [PDF]

, 2008
The Lockerbie case has already contributed significantly to the jurisprudence of the law of evidence. Al Megrahi v HM Advocate continues in that vein, shedding some light on how the law relating to public interest immunity now operates following ...
Davidson, Fraser
core   +1 more source

Neurovascular and immune factors of vulnerability of substantia nigra dopaminergic neurons in non-human primates

npj Parkinson's Disease
Dopaminergic neurons in the ventral tier of the substantia nigra pars compacta (SNc) degenerate prominently in Parkinson’s disease (PD), while those in the dorsal tier and ventral tegmental area are relatively spared.
Tiziano Balzano, Natalia López-González del Rey, Noelia Esteban-García, Alejandro Reinares-Sebastián, José A. Pineda-Pardo, Inés Trigo-Damas, José A. Obeso, Javier Blesa   +7 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Comparaison entre les dysosmies post-COVID-19 et celles de la maladie de Parkinson

Glossa
Contexte. Les troubles olfactifs, longtemps considérés comme secondaires, ont connu une nouvelle visibilité à la suite de la pandémie de COVID-19. Parallèlement, les dysosmies sont aujourd’hui reconnues comme un signe prodromique majeur dans la maladie ...
Léa Guerra, Laurane Bessi, Corentin Gaillard, Yoran Marchi, Thomas Radulesco, Justin Michel, Jean-Philippe Azulay, Emmanuelle Albert, Stephan Grimaldi   +8 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Calbindin and Girk2/Aldh1a1 define resilient vs vulnerable dopaminergic neurons in a primate Parkinson’s disease model

npj Parkinson's Disease
The differential vulnerability of dopaminergic neurons of the substantia nigra pars compacta (SNc) is a critical and unresolved question in Parkinson´s disease.
Natalia López-González del Rey, Nagore Hernández-Pinedo, Megan Carrillo, María del Cerro, Noelia Esteban-García, Inés Trigo-Damas, Mariana H. G. Monje, José L. Lanciego, Carmen Cavada, José A. Obeso, Javier Blesa   +10 more
doaj   +1 more source

Long-Term Survival in Hepatocellular Carcinoma following Second-Line Tumor Treating Fields Therapy and Sorafenib: A Case Report

Case Reports in Oncology
Introduction: Hepatocellular carcinoma (HCC) is an aggressive solid tumor associated with high mortality. Surgery is the main treatment consideration for early disease, but patients who present with locally advanced or metastatic HCC at diagnosis have ...
Marisa Torres Velasco, Rafael Álvarez Gallego, Paloma Peinado, Cesar Muñoz Gregorio, Lisardo Ugidos, Marcial García Morillo, Emilio Vicente, Yolanda Quijano, Susana Prados, Enrique de la Fuente, Antonio Cubillo Gracián   +10 more
doaj   +1 more source

Análisis clínico, epidemiológico y evolutivo del paciente ingresado COVID19 sobre una población mayoritariamente vacunada

Galicia Clínica, 2022
Análisis clínico, epidemiológico y evolutivo del paciente ingresado por COVID19 en el Servicio de Medicina Interna del Hospital HM del Área Sanitaria de A Coruña.
Ignacio Ramil Freán, Maria Fernandez López, Martin Vidal Vazquez   +2 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

HM&Co Lab

, 2017
Presentation of the research, innovation and outreach activities of the Hydrology Meteorology and Complexity Lab at École des Ponts ParisTech.Video: Rosa Vicari / HM&Co - École des Ponts ParisTechImages: Abdellah Ichiba, Auguste Gires, BlueGreenDream, HM&
Vicari, Rosa
core   +1 more source