Genotype-guided comparison of VEN/HMA versus intensive chemotherapy in newly diagnosed intermediate-risk AML: a multicenter real-world study. [PDF]
Chen X +10 more
europepmc +1 more source
An emerging triplet option for newly diagnosed <i>FLT3</i>-mutated acute myeloid leukemia. [PDF]
Boussi L, Goldberg AD.
europepmc +1 more source
Mismatch screening in Nicotiana benthamiana to explore Pik-1/Pik-2 paired NLR platforms for receptor engineering. [PDF]
Xi Y, Banfield MJ.
europepmc +1 more source
Mitochondria of a human skeletal muscle cell line associate with the parasitophorous vacuoles of three archetypal lineages of <i>Toxoplasma gondii</i> and influence fatty acid import. [PDF]
Christiansen C, Laue M, Blume M.
europepmc +1 more source
A retrospective analysis of upfront treatment strategies in chronic myelomonocytic leukemia: impact on survival and response patterns. [PDF]
Yousuf M +14 more
europepmc +1 more source
Related searches:
Outcomes in AML patients receiving HMA + venetoclax combination with prior HMA exposure.
Journal of Clinical Oncology, 2021e19011 Background: Venetoclax (Ven) is a BCL-2 inhibitor approved in combination with hypomethylating agents (HMAs) in newly diagnosed AML patients who are not candidates for intensive induction based on impressive response rates (CR+CRi of 66.4%) and median overall survival (14.7 months) compared to HMA therapy alone (DiNardo CD, NEJM, 2020).
Bakos Keegan Jonathan +8 more
openaire +1 more source
Novel therapies upon failure of HMA plus venetoclax
Hematology, 2023Abstract The efficacy and tolerability of the combination of hypomethylating agents with venetoclax (HMA-VEN) in patients with newly diagnosed acute myeloid leukemia has been a practice-changing milestone in the field. However, treatment failure and relapse remain major barriers to prolonged survival.
Onyee, Chan, Alison R, Walker
openaire +2 more sources

