Results 41 to 50 of about 2,796 (260)

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

AI‐Assisted Engineering of Glycyrrhizic Acid/Simvastatin Nanocrystals for Multifunctional Treatment of Bacterial Osteomyelitis

Advanced Science, EarlyView.
Through AI‐assisted screening from FDA‐approved API to overcome the limitations of bacterial osteomyelitis treatment, glycyrrhizic acid and simvastatin are identified as a multifunctional combination capable of self‐assembling into mechanism‐targeting nanocrystals that effectively neutralize reactive oxygen species, suppress M1 macrophage polarization,
Yu Han, Yao Zhao, Chengbo Yang, Miao Niu, Jun Dai, Quanxin Ning, Kai Xiao, Jinzheng Liang, Wensheng Zhang, Liang Wang, Dan Shao, Dongsong Li   +11 more
wiley   +1 more source

Helicobacter pylori virulence genes of minor ethnic groups in North Thailand

Gut Pathogens, 2017
Background There are few studies analyzed concurrently the prevalence and genotypes of Helicobacter pylori infection with the ancestor origins from different ethnics, especially with including minority groups.
Phawinee Subsomwong, Muhammad Miftahussurur, Ratha-korn Vilaichone, Thawee Ratanachu-ek, Rumiko Suzuki, Junko Akada, Tomohisa Uchida, Varocha Mahachai, Yoshio Yamaoka   +8 more
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Hmong-American K-12 Students and the Academic Skills needed for a College Education: A Review of the Existing Literature and Suggestions for Future Research [PDF]

Hmong Studies Journal, 2004
This research literature review article examines the factors that affect academic success or failure of Hmong-American K-12 students to provide some insights into the academic challenges and complexity they still face today in the American educational ...
Christopher T. Vang
doaj  

Demographic changes and marker properties affect detection of human population differentiation

BMC Genetics, 2007
Background Differentiating genetically between populations is valuable for admixture and population stratification detection and in understanding population history.
Sanichwankul Kittipong, Thavichachart Nuntika, Raaum Ryan L, Yang Bao-Zhu, Sughondhabirom Atapol, Malison Robert T, Listman Jennifer B, Kranzler Henry R, Tangwonchai Sookjaroen, Mutirangura Apiwat, Disotell Todd R, Gelernter Joel   +11 more
doaj   +1 more source

Medical Mistrust and Discrimination in Health Care: A Qualitative Study of Hmong Women and Men [PDF]

Journal of Community Health, 2011
Low rates of breast and cervical cancer screening among Hmong women have been documented. Mistrust of Western medicine and the health care system, as well as experiences of discrimination in health care, may be barriers to seeking health care for this population.
Sheryl, Thorburn, Jennifer, Kue, Karen Levy, Keon, Patela, Lo   +3 more
openaire   +2 more sources

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

Advanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen, Bapan Biswas, Apinya Ngoipala, Julia Wiktor, Ujjwal Pal, Shalini Singh   +5 more
wiley   +1 more source

Divergent Synthesis of Möbius and Hückel N‐Heterocycloarenes From a Common Macrocyclic Backbone

Angewandte Chemie, EarlyView.
In the divergent synthesis of Möbius and Hückel N‐heterocycloarenes from a common macrocyclic precursor, the annulation reaction dictates topology: Scholl reaction gives Möbius topology, while InCl3‐mediated alkyne annulation gives Hückel topology. The Möbius N‐heterocycloarene is unevenly contorted as revealed by crystal structure, and the Hückel N ...
Han Chen, Huishu Ma, Daiyue Yang, Zheng Zhou, Xiao Chen, Zhifeng Huang, Qian Miao   +6 more
wiley   +2 more sources