Results 131 to 140 of about 12,381 (200)

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1686-1701, October 2026.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Engineered palladium nanostructures dimensionality mechanistic analysis of structure property relationships electrocatalytic performance of formic acid oxidation reaction

Chemical Engineering Journal. Green and Sustainable
Controlled dimensionality in Palladium nanostructures offers a powerful lever for optimizing the formic acid oxidation reaction in fuel cell applications.
Bulti Pramanick
doaj   +1 more source

Structure and Expression of Sibling-Species Hmr⁺ Transgenes

, 2013
(A) Diagram of Hmr+ transgenic constructs. The Hmr gene structure is shown, with the rightward arrow indicating the predicted translation start site. Sibling-species constructs used in this study are shown, together with D.
Aaron M Tarone (56377), Daniel A Barbash (31884), Philip Awadalla (21228)   +2 more
core   +1 more source

Survival outcomes and treatment patterns in myelofibrosis in the JAK inhibitor era

British Journal of Haematology, Volume 209, Issue 4, Page 1715-1724, October 2026.
Summary Data on real‐world survival and treatment patterns in large, unselected myelofibrosis (MF) cohorts remain limited. We analysed 1649 patients with MF diagnosed from 2010 onwards and included in the Spanish Myelofibrosis Registry across 64 centres. Janus kinase (JAK) inhibitors were administered to approximately half of the patients.
Juan‐Carlos Hernández‐Boluda, Eduardo Arellano‐Rodrigo, Manuel Pérez‐Encinas, José‐María Raya, María‐Teresa Gómez‐Casares, Francisca Ferrer‐Marín, Alberto Hernández‐Sánchez, María‐Laura Fox, Anna Angona, Beatriz Cuevas, María‐Isabel Mata‐Vázquez, Rosa Ayala, Natalia de las Heras, Elvira Mora, Valentín García‐Gutiérrez, Alicia Senín, Jasson Villarreal, Blanca Xicoy, Raúl Pérez‐López, María García‐Fortes, Sonia González de Villambrosia, Elena Magro, María‐José Ramírez, Paula Gómez, Angel Ramírez‐Payer, Clara Martínez‐Valverde, Lucía Pérez‐Lamas, Carmen García‐Hernández, Mercedes Gasior, Luis‐Miguel Juárez‐Salcedo, Francisco Ibáñez, María‐Luisa Antelo, Lucía Guerrero, Alberto Alvarez‐Larrán, Arturo Pereira, on behalf of the Spanish MPN Group (GEMFIN)   +35 more
wiley   +1 more source

Dextrosinistral reading of SMILES notation: Investigation into origin of non-sense code from string manipulations

Digital Chemical Engineering
The SMILES notation provides a digital way to represent any chemical structure in the form of a string of ASCII characters, therefore, a preferred data medium for machine learning models.
Anup Paul
doaj   +1 more source

Replication and Silencing at the Hmr-E Compound Origin in Saccharomyces Cerevisiae

, 2002
This study investigated the relationship between two distinct biological processes, replication and silencing, as they occur from the HMR locus. Within this locus, an 868 base pair (bp) region termed HMR-E functions as both a silencer and an origin of ...
Hurst, Simi Thomas
core  

Wearable Electronic Monitoring of Vital Signs in Hospitalised Adults: A Nursing Focused Scoping Review of Clinical, Economic and Implementation Outcomes

Journal of Advanced Nursing, Volume 82, Issue 10, Page 9061-9111, October 2026.
ABSTRACT Aim To synthesise evidence on wearable devices for continuous vital signs monitoring in adult hospital inpatients, focusing on clinical effectiveness, nursing perspectives, workflow impact, patient experience and resource implications. Design Scoping review.
Sian Myfanwy Shaw, Sophie Bethan Shaw, Gillian Janes   +2 more
wiley   +1 more source

Soluble guanylyl cyclase activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress

, 2007
Many vascular diseases are characterized by increased levels of ROS that destroy the biological activity of nitric oxide and limit cGMP formation. In the present study, we investigated the cGMP-forming ability of HMR-1766 in cells exposed to oxidative ...
Kotanidou, A., Dalkas, G., Spyroulias, G., Van Eickels, M., Pyriochou, A., Papapetropoulos, A., Zhou, Z., Roussos, C.   +7 more
core  

Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report

Journal of Pharmacy
Introduction: Home Medication Review (HMR) is crucial for optimising medication use and improving patient’s outcomes. Despite its potential benefits, HMR implementation in rural areas faces challenges.
Norny Syafinaz Ab Rahman, Nur Alyaa Anisa Mat Harom, Nor Ilyani Mohamed Nazar   +2 more
doaj  

In Vitro Pharmacodynamic Studies of Activities of Ketolides HMR 3647 (Telithromycin) and HMR 3004 against Extracellular or Intracellular Helicobacter pylori

, 2001
The pharmacodynamic properties of the ketolides HMR 3647 (telithromycin) and HMR 3004 were studied against Helicobacter pylori .
I. Gustafsson, L. Engstrand, Gustafsson, I, O. Cars, Cars, O, Engstrand, L,   +5 more
core   +1 more source