Results 61 to 70 of about 9,123 (196)

In Vitro Pharmacodynamic Studies of Activities of Ketolides HMR 3647 (Telithromycin) and HMR 3004 against Extracellular or Intracellular Helicobacter pylori [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2001
ABSTRACT The pharmacodynamic properties of the ketolides HMR 3647 (telithromycin) and HMR 3004 were studied against Helicobacter pylori . Both ketolides showed a pronounced concentration-dependent killing, a significant postantibiotic effect, a long postantibiotic sub-MIC effect, and a reduction of ...
I, Gustafsson, L, Engstrand, O, Cars
openaire   +2 more sources

Microcirculation function assessment in acute myocardial infarction: A systematic review of microcirculatory resistance indices

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundUp to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes.
Marta Silva   +12 more
doaj   +1 more source

Regulating Interfacial Water Structure on CoNi/MoN Heterostructures Boosts Electrocatalytic Nitrate Reduction to Ammonia

open access: yesCarbon Energy, EarlyView.
The CoNi/MoN interface effect induces electron transfer from CoNi species to MoN nanosheets, in which electron‐enriched CoNi/MoN interface captures K+ to form K+‐H2O, facilitating H2O dissociation to provide *H for accelerating hydrogenation steps, while electron‐deficient CoNi nanoparticles enhances the NO3− adsorption and reduces the free energy ...
Xue Chen   +8 more
wiley   +1 more source

Identification and validation of a histone modification-related gene signature to predict the prognosis of multiple myeloma

open access: yesFrontiers in Genetics
BackgroundMultiple myeloma (MM) is an incurable plasma cell malignancy with high heterogeneity. Current staging systems, including the International Staging System (ISS) and Revised ISS (R-ISS), have limited prognostic accuracy. Given the role of histone
Juan Lyu   +5 more
doaj   +1 more source

A Selectfluor‐based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications

open access: yesChemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.
Starting from carboxylic acids and Selectfluor‐derivatives, functionalized diazabicyclooctanes can be obtained via a novel Polonovski‐type rearrangement proceeding under mild reaction conditions. Besides their use in organic synthesis the unique structure and reactivity of the rearrangement products enables applications in medicinal chemistry ...
Jakob Kuhn   +5 more
wiley   +1 more source

Long term follow-up of drug resistant and drug susceptible tuberculosis contacts in a Low incidence setting

open access: yesBMC Infectious Diseases, 2012
Background Studies examining the transmission of multidrug-resistant tuberculosis (MDR-TB) strains have yielded conflicting results. Methods We examined transmission of MDR-TB strains using contact tracing data from a low incidence setting.
Johnston James   +6 more
doaj   +1 more source

Distinguishing between recruitment and spread of silent chromatin structures in Saccharomyces cerevisiae

open access: yeseLife, 2022
The formation of heterochromatin at HML, HMR, and telomeres in Saccharomyces cerevisiae involves two main steps: the recruitment of Sir proteins to silencers and their spread throughout the silenced domain.
Molly Brothers, Jasper Rine
doaj   +1 more source

Patterns of psychopathology and personal strengths among youth in psychiatric care

open access: yesJCPP Advances, EarlyView.
Abstract Background The American Academy of Pediatrics and the American Academy of Child and Adolescent Psychiatry have declared a National State of Emergency in Children's Mental Health, calling for improved approaches to address youth mental health.
Logan R. Cummings   +78 more
wiley   +1 more source

Intraoperative hemodynamic imbalance quantification: clinical validation of heart rate to mean blood pressure ratio in predicting myocardial injury after noncardiac surgery

open access: yesBMC Cardiovascular Disorders
Background The effects of isolated heart rate (HR) and mean blood pressure (MBP) on myocardial injury after noncardiac surgery (MINS) have been investigated, but the combined impact of intraoperative HR and MBP remains unclear. This study aimed to assess
Yuanjun Zhou   +5 more
doaj   +1 more source

Chemoreactome analysis of 7-hydroxymatairesinol, 17-estradiol, phytoestrogen β-sitosterol and epigallocatechin-3-gallate

open access: yesАкушерство, гинекология и репродукция, 2020
The results of the evaluation of 7-hydroximatairesinol (7-HMR) properties in comparison with control molecules (17-estradiol, phytoestrogen β-sytostirol, epigallocatechin-3-gallate) are presented.
I. Yu. Torshin   +3 more
doaj   +1 more source

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