Results 51 to 60 of about 17,594 (264)

Ravulizumab for relapse prevention in AQP4-IgG–positive neuromyelitis optica spectrum disorder: a 2-year follow-up case report

Frontiers in Medicine
BackgroundNeuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system, distinct from multiple sclerosis, characterized by severe inflammatory attacks targeting the optic nerves, spinal cord, and brainstem ...
Nabil Akkawi, Elkhansa Hassabo Mohamed, Ahmed Shatila   +2 more
doaj   +1 more source

Molecular Imaging: A Promising Tool to Monitor Islet Transplantation

Journal of Transplantation, 2011
Replacement of insulin production by pancreatic islet transplantation has great potential as a therapy for type 1 diabetes mellitus. At present, the lack of an effective approach to islet grafts assessment limits the success of this treatment.
Ping Wang, Zdravka Medarova, Anna Moore
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

EFFECT OF SPECIALTY ORIENTED HOSPITAL MANAGEMENT SYSTEM (HMS) ON QUALITY OF ELECTRONIC MEDICAL RECORDS (EMRs) IN 2 TERTIARY CARE HOSPITALS

Pakistan Armed Forces Medical Journal, 2018
Objective: To assess effect of “specialty oriented HMS software” on “quality of EMRs”. Study Design: Comparative interventional study. Place and Duration of Study: Obstetrics Out Patient Department (OPD) of Pak Emirates Military Hospital (PEMH ...
Eisha Mansoor, Nagin Anjum, Tahir Mahmood Butt, Mansoor Tariq   +3 more
doaj  

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life

Nature Communications
Specialized ribosomes help determine which proteins are synthesized, however, the influence of age on ribosome heterogeneity and whether dysregulation of this process drives organismal aging is unknown.
M. Hafiz Rothi, Gautam Chandra Sarkar, Joseph Al Haddad, Wayne Mitchell, Kejun Ying, Nancy Pohl, Roberto G. Sotomayor-Mena, Julia Natale, Scarlett Dellacona, Vadim N. Gladyshev, Eric Lieberman Greer   +10 more
doaj   +1 more source

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells

Nature Communications, 2017
While circulating DNA has been extensively explored as a potential cancer biomarker, RNA potential has been overlooked so far. Here the authors present a comprehensive analysis of extracellular RNA secreted by glioblastoma cells that could prove a ...
Zhiyun Wei, Arsen O. Batagov, Sergio Schinelli, Jintu Wang, Yang Wang, Rachid El Fatimy, Rosalia Rabinovsky, Leonora Balaj, Clark C. Chen, Fred Hochberg, Bob Carter, Xandra O. Breakefield, Anna M. Krichevsky   +12 more
doaj   +1 more source

Extreme‐Thickness Meta‐Membrane for Controlling Terahertz Vectorial Beams

Advanced Science, EarlyView.
We propose ultra‐thin (λ/30) transmissive terahertz metasurfaces combining near‐field resonant and detour phases in coupled‐slit meta‐atoms, enabling continuous phase and polarization control beyond conventional designs. Based on leaky‐mode theory, scalar and vectorial terahertz Bessel beams at 0.39 THz are experimentally demonstrated, with ...
Yufei Song, Yixiang Xu, Yikai Xu, Yuanxi Liu, Shaojie Ma, Qiong He, Zhuo Wang, Lei Zhou   +7 more
wiley   +1 more source

What do EEG and MRI connectivity measure? Evaluating human brain connectivity with TMS-EEG

Brain Stimulation, 2023
Recep Ozdemir, Davide Momi, Jord Vink, Debby Klooster, Bernard Chang, Alvaro Pascual-Leone, Emiliano Santarnecchi, Mouhsin Shafi   +7 more
doaj   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source