Results 51 to 60 of about 17,319 (267)
Advanced Science, EarlyView.We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2018 Objective: To assess effect of “specialty oriented HMS software” on “quality of EMRs”. Study Design: Comparative interventional study. Place and Duration of Study: Obstetrics Out Patient Department (OPD) of Pak Emirates Military Hospital (PEMH ...
Eisha Mansoor +3 more
doaj
The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life
Nature CommunicationsSpecialized ribosomes help determine which proteins are synthesized, however, the influence of age on ribosome heterogeneity and whether dysregulation of this process drives organismal aging is unknown.
M. Hafiz Rothi +10 more
doaj +1 more source
Molecular Imaging: A Promising Tool to Monitor Islet Transplantation
Journal of Transplantation, 2011 Replacement of insulin production by pancreatic islet transplantation has great potential as a therapy for type 1 diabetes mellitus. At present, the lack of an effective approach to islet grafts assessment limits the success of this treatment.
Ping Wang, Zdravka Medarova, Anna Moore
doaj +1 more source
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Mechanozyme: An Artificial Enzyme With a Mechanophore Framework
Advanced Science, EarlyView.Mechanical destabilization of a G‐quadruplex mechanophore in a DNAzyme markedly boosts its catalytic activity, demonstrating “mechanozymes” as artificial enzymes whose functions are modulated by mechanical stress exerted by ultrasonication. This mechanozyme principle is broadly applicable to control biomolecular activities.
Jiahao Ji +7 more
wiley +1 more source
Advanced Science, EarlyView.SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng +6 more
wiley +1 more source
What do EEG and MRI connectivity measure? Evaluating human brain connectivity with TMS-EEG
Brain Stimulation, 2023 Recep Ozdemir +7 more
doaj +1 more source
Onset timing of letter processing in auditory and visual sensory cortices
Frontiers in Integrative NeuroscienceHere, we report onset latencies for multisensory processing of letters in the primary auditory and visual sensory cortices. Healthy adults were presented with 300-ms visual and/or auditory letters (uppercase Roman alphabet and the corresponding auditory ...
Tommi Raij +10 more
doaj +1 more source
Advanced Science, EarlyView.Integrating experimental insights with molecular dynamics simulations, we establish an advanced mathematical model for fluids confined in sub‐10‐nm channels, enabling quantitative prediction of interfacial layer thickness and viscosity by accounting for channel material, temperature, and fluid properties.
Xiang Zhang +3 more
wiley +1 more source