Results 81 to 90 of about 37,422 (302)

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

Effect of Template Removal Methods on Physical Properties and Catalytic Performance of Co-HMS

, 2009
With Co(OAc)(2) as Cc source and hexadecylamine (HDA) as template, cobalt-containing hexagonal mesoporous silicas (Co-HMS) was successfully synthesized by a one-step co-condensation route at ambient temperature.
Chen Chen, Wei Zhang, Chen, Chen, Xu, Jie, Gao, Jin, Jin Gao, Zhang, Wei, Qiaohong Zhang, 徐杰, Jie Xu, Zhang, Qiaohong   +10 more
core   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

HMS i hjemmesykepleien : hvordan ivaretas arbeidsmiljøet [PDF]

, 2012
Formålet med oppgaven har vært å se på HMS- systemet i hjemmesykepleien. Oppgaven har sett på hvilke arbeidsmiljømessige utfordringer to soner i hjemmesykepleien har i en og samme kommune.
Helliesen, Hege
core  

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Additive manufacturing of metallic heterostructured materials: from 1D to 4D

Materials Research Letters
Additive manufacturing (AM) offers unique opportunities for the design and fabrication of metallic heterostructured materials (HMs) with complex geometries and programable spatial heterogeneity. Unlike traditional HMs fabrication processes, AM progresses
Xiaoyi Xu, Tian-Shu Liu, Yongjing Yang, Chaolin Tan   +3 more
doaj   +1 more source

HMS og Internkontrollforskriften. Formelt eller reelt implementert? [PDF]

, 2016
Denne masteroppgaven er en studie av helse-, miljø- og sikkerhet (HMS) i Forsvaret, med utgangspunkt i norske myndigheters fastsettelse av hvordan arbeidet skal følges opp og det ansvaret som ligger på virksomhetsledere.
Bexrud, Erik, Ottosen, Emil
core  

Stakeholders’ groups in HMS.

, 2015
Stakeholders’ groups in HMS.
Muhammad Imran Babar (708822), Dayang N. A. Jawawi (708824), Masitah Ghazali (708823), Kashif Bin Zaheer (708825)   +3 more
core   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source