Results 101 to 110 of about 45,071 (126)

Membranes. [PDF]

open access: yesCurr Opin Cell Biol, 1992
europepmc   +1 more source

HN1 interacts with γ-tubulin to regulate centrosomes in advanced prostate cancer cells [PDF]

open access: yesCell Cycle, 2021
Prostate cancer is one of the most common cancer for men worldwide with advanced forms showing supernumerary or clustered centrosomes. Hematological and neurological expressed 1 (HN1) also known as Jupiter Microtubule Associated Homolog 1 (JPT1) belongs ...
Lokman VARIŞLI   +2 more
exaly   +3 more sources

HN1 Is Enriched in the S-Phase, Phosphorylated in Mitosis, and Contributes to Cyclin B1 Degradation in Prostate Cancer Cells [PDF]

open access: yesBiology, 2023
HN1 has previously been shown as overexpressed in various cancers. In Prostate cancer, it regulates AR signaling and centrosome-related functions. Previously, in two different studies, HN1 expression has been observed as inversely correlated with Cyclin ...
Aadil Javed   +2 more
exaly   +2 more sources

HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity

open access: yesMolecular Cancer, 2017
Background Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism have not been well understood. Methods To study the role of HN1 in the initiation and
Ying Zhao, Pian Liu
exaly   +2 more sources

Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells

open access: yesMolecular and Cellular Endocrinology, 2012
We recently reported that hematological and neurological expressed 1 (HN1) is a ubiquitously expressed, EGF-regulated gene. Expression of HN1 in prostate cell lines down-regulates PI3 K-dependent Akt activation.
Lokman VARIŞLI   +2 more
exaly   +2 more sources

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