Results 101 to 110 of about 51,852 (122)

HN1 interacts with γ-tubulin to regulate centrosomes in advanced prostate cancer cells [PDF]

Cell Cycle, 2021
Prostate cancer is one of the most common cancer for men worldwide with advanced forms showing supernumerary or clustered centrosomes. Hematological and neurological expressed 1 (HN1) also known as Jupiter Microtubule Associated Homolog 1 (JPT1) belongs ...
Bilge Esin Öztürk, Aadil Javed, Gençer Kaan Akyuz   +2 more
exaly   +3 more sources

HN1 Is Enriched in the S-Phase, Phosphorylated in Mitosis, and Contributes to Cyclin B1 Degradation in Prostate Cancer Cells [PDF]

Biology, 2023
HN1 has previously been shown as overexpressed in various cancers. In Prostate cancer, it regulates AR signaling and centrosome-related functions. Previously, in two different studies, HN1 expression has been observed as inversely correlated with Cyclin ...
Bilge Esin Öztürk, Aadil Javed, Lokman Varişli   +2 more
exaly   +2 more sources

HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity

Molecular Cancer, 2017
Background Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism have not been well understood. Methods To study the role of HN1 in the initiation and
Pian Liu, Ying Zhao, Shi Lu
exaly   +2 more sources

HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis

Cytoskeleton
Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule-associated protein.
Kemal Sami Korkmaz
exaly   +2 more sources

Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells

Molecular and Cellular Endocrinology, 2012
We recently reported that hematological and neurological expressed 1 (HN1) is a ubiquitously expressed, EGF-regulated gene. Expression of HN1 in prostate cell lines down-regulates PI3 K-dependent Akt activation.
Bilge Debelec Bütüner, Lokman Varişli, Burcu Erbaykent Tepedelen   +2 more
exaly   +2 more sources

HN1 is a novel dedifferentiation factor involved in regulating the cell cycle and microtubules in SH‐SY5Y neuroblastoma cells

Journal of Cellular Biochemistry
Hematological and neurological expressed 1 (HN1), encoding a small protein, has been recently explored in different cancers owing to its higher expression in tumor samples as compared to adjacent normal.
Gülseren Ozduman, Kemal Sami Korkmaz, Tilbe Ozar   +2 more
exaly   +2 more sources

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The HN1 / HMGB1 axis promotes the proliferation and metastasis of hepatocellular carcinoma and attenuates the chemosensitivity to oxaliplatin

FEBS Journal, 2022
Yarui Li, Yiguang Lin, Shuixiang He
exaly  

Hematological and neurological expressed 1 (HN1) activates c‐Myc signaling by inhibiting ubiquitin‐mediated proteasomal degradation of c‐Myc in hepatocellular carcinoma

Cell Biology International, 2023
Jutao Feng
exaly