Results 21 to 30 of about 36,900 (116)

HN1 is a novel dedifferentiation factor involved in regulating the cell cycle and microtubules in SH‐SY5Y neuroblastoma cells

Journal of Cellular Biochemistry
Hematological and neurological expressed 1 (HN1), encoding a small protein, has been recently explored in different cancers owing to its higher expression in tumor samples as compared to adjacent normal.
Tilbe Özar, Aadil Javed, Gülseren Özduman, K. Korkmaz   +3 more
semanticscholar   +1 more source

HN1 expression contributes to mitotic fidelity through Aurora A‐PLK1‐Eg5 axis

Cytoskeleton
Hematological and neurological expressed 1 (HN1) is homolog of Jupiter protein from Drosophila melanogaster where it functions as a microtubule‐associated protein.
Gülseren Özduman, Faruk Şimşek, Aadil Javed, K. Korkmaz   +3 more
semanticscholar   +1 more source

HNRNPA1-mediated 3′ UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes

Aging, 2019
Cellular senescence has been regarded as a mechanism of tumor suppression. Studying the regulation of gene expression at various levels in cell senescence will shed light on cancer therapy.
Qi Jia, H. Nie, YU Peng, Baiyun Xie, Chenji Wang, Fu Yang, Gang Wei, T. Ni   +7 more
semanticscholar   +1 more source

HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity

Molecular Cancer, 2017
Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism have not been well understood.
Chen Zhang, Bingfei Xu, Shi Lu, Ying Zhao, Pian Liu   +4 more
semanticscholar   +1 more source

Increased expression of hematological and neurological expressed 1 (HN1) is associated with a poor prognosis of hepatocellular carcinoma and its knockdown inhibits cell growth and migration partly by down‐regulation of c‐Met

Kaohsiung Journal of Medical Sciences, 2019
Hematologic and neurological expression 1 (HN1) has been reported to involved in certain cancers, but its role in hepatocellular carcinoma (HCC) is largely unknown. The contribution of HN1 to HCC progression was investigated in the present study.
Jiajie Chen, Xu Sun, Qi-qi Mao, X. Jiang, Xianguang Zhao, Wei-Jia Xu, L. Zhong   +6 more
semanticscholar   +1 more source

Efficient, diode-pumped, high-power (>300W) cryogenic Yb:YLF laser with broad-tunability (995-1020.5 nm): investigation of E//a-axis for lasing.

Optics Express, 2019
We present, what is to our knowledge, the first detailed lasing investigation of cryogenic Yb:YLF gain media in the E//a-axis. Compared to the usually employed E//c-axis, the a-axis of Yb:YLF provides a much broader and smooth gain profile, but this ...
U. Demırbas, H. Cankaya, Jelto Thesinga, F. Kärtner, M. Pergament   +4 more
semanticscholar   +1 more source

Hematological and Neurological Expressed 1 (HN1): a predictive and pharmacodynamic biomarker of metformin response in endometrial cancers

bioRxiv, 2019
Preoperative use of metformin in obese women with endometrioid endometrial cancer (EEC) reduces tumor proliferation and inhibits the mammalian target of rapamycin (mTOR) pathway, though is only effective in select cases.
N. Bateman, P. Teng, Erica Hope, B. Hood, J. Oliver, W. Ao, Ming Zhou, Guisong Wang, D. Tommarello, K. Wilson, K. Conrads, C. Hamilton, K. Darcy, Y. Casablanca, G. L. Maxwell, V. Bae-Jump, T. Conrads   +16 more
semanticscholar   +1 more source

Clinical outcomes in 995 unselected real-world patients treated with an ultrathin biodegradable polymer-coated sirolimus-eluting stent: 12-month results from the FLEX Registry

BMJ Open, 2016
Objectives To evaluate, in the FLEX Registry, clinical outcomes of an ultrathin (60 µm) biodegradable polymer-coated Supraflex sirolimus-eluting stent (SES) for the treatment of coronary artery disease. Additionally, to determine the vascular response to
P. Lemos, P. Chandwani, Sudheer Saxena, P. Ramachandran, A. Abhyankar, C. Campos, J. Marchini, M. Galon, P. Verma, M. Sandhu, Nikhil Parikh, A. Bhupali, Sharad Jain, J. Prajapati   +13 more
semanticscholar   +1 more source

“El presente es de lucha, el futuro socialista”

Revista Controversia, 2008
Este artículo pretende dar cuenta de la conformación del “campo socialista” en Colombia, en los años 70 del siglo pasado, cuando contribuyó a fomentar debates políticos significativos dentro de la izquierda del país. Este lapso está comprendido entre dos
Martha Cecilia García
doaj  

Experiencias internacionales de procesos de paz y de transición hacia la democracia: La incidencia del movimiento sindical

Revista Controversia, 2016
Como manera de aportar a una reflexión sobre los posibles caminos que se pueden abrir en Colombia, luego de la firma del Acuerdo de Paz entre el Gobierno y las Farc-EP, y la apertura de negociaciones de paz entre el mismo gobierno y el ELN, el presente ...
Kjeld Jakobsen
doaj