Results 161 to 170 of about 46,426 (253)

A Generalizable Transformer Framework for Gene Regulatory Network Inference from Single‐Cell Transcriptomes

Advanced Intelligent Systems, EarlyView.
FTGRN introduces an LLM‐enhanced framework for gene regulatory network inference through a two‐stage workflow. It combines a Transformer‐based model, pretrained on GPT‐4 derived gene embeddings and regulatory knowledge, with a fine‐tuning stage utilizing single‐cell RNA‐seq data.
Guangzheng Weng, Hyobin Kim, Patrick Martin, Junil Kim, Tae‐Hyung Kim, Gi‐Hoon Nam, Dongha Kim, Kyoung Jae Won   +7 more
wiley   +1 more source

Chromosome-level genome assembly of triploid Cyperus rotundus uncovers allelic expression patterns and herbicide resistance mechanisms. [PDF]

Plant Commun
Wu L, Luo Z, Lu Y, Li J, Liu M, Cai H, Zhao S, Huang J, Yi L, He S, Bai L, Pan L.   +11 more
europepmc   +1 more source

Nonplanar Atomic Layer Deposition (ALD)‐Niobium Oxide (NbOx) Neurons for Oscillatory Neural Network Applications

Advanced Intelligent Systems, EarlyView.
This article presents a nonplanar niobium oxide (NbOx) neuron device fabricated using an atomic layer deposition (ALD) method for use in oscillatory neural networks (ONNs). Potentially, such nonplanar geometry allows for high‐density arrays. The desired threshold switching (TS) characteristics are achieved through an interfacial method using a thin ...
Jaehyun Moon, Kitae Kim, Jihyun Kim, Soohyung Park, Yeonjin Yi, Jiyong Woo, Seung‐Youl Kang   +6 more
wiley   +1 more source

Photon-Counting Micro-CT for Bone Morphometry in Murine Models. [PDF]

Tomography
Nadkarni R, Han ZY, Allphin AJ, Clark DP, Badea A, Badea CT.   +5 more
europepmc   +1 more source

Terrestrial Cyborg Insects for Real‐Life Applications

Advanced Intelligent Systems, EarlyView.
This article reviews the development of terrestrial cyborg insects from their emergence in 1997 to mid‐2025, examining three key aspects: locomotion control methods, associated challenges with proposed solutions, and practical applications. Framing these biohybrid systems as insect‐scale mobile robots, the review provides foundational insights for new ...
Hai Nhan Le, Lachlan Fitzgerald, Phuoc Thien Phan, Robbie Wilson, Christofer Clemente, Huu Duoc Nguyen, Hirotaka Sato, Hoang‐Phuong Phan, Peter Ross McAree, Thanh Nho Do, Tat Thang Vo‐Doan   +10 more
wiley   +1 more source

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Dendrocin ZM1 Nanoconjugates with Carbon Quantum Dots: A ROS-Generating Platform for Combating Multidrug-Resistant Bacteria. [PDF]

Int J Nanomedicine
Seyedjavadi SS, Zare-Zardini H, Sharif Bakhtiar L, Razzaghi-Abyaneh M, Navidinia M, Rahmandoust M, Goudarzi M.   +6 more
europepmc   +1 more source

Further Detail Concerning the Deep Learning Model for Mortality After Total Gastrectomy

Annals of Gastroenterological Surgery, EarlyView.
Kentaro Goto, Haruku Fujita, Ryohei Onishi, Nobuaki Hoshino, Koya Hida   +4 more
wiley   +1 more source

To Raise or Not to Raise: An Experimental Test of Community Support for Increasing the Minimum Age of Criminal Responsibility in New South Wales, Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT While research has identified a disconnect between the minimum age of criminal responsibility (MACR) and public perceptions of criminal culpability among young people, no study has examined how offender characteristics influence support for reform using an experimental design. To address this, this study presents the first experimental test of
Cameron T. Langfield, Natalia Hanley, Jason L. Payne, Helen Simpson   +3 more
wiley   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source