Results 91 to 100 of about 12,097 (249)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
NingunaThe Stora Brunneby hoard of 17 solidi with a terminus post quem of 451 is presented and analysed as a preliminary result of the LEO Project. Its type composition and the coins' average weight are quite unusual and support that he Stora Brunneby ...
López Sánchez, Fernando +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Bessie Hoard, Jan 3, 1935. Label on original sleeve : Bessie Hoard, Jan 3, 1935https://mds.marshall.edu/carl_photograph_collection/1128/thumbnail ...
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
data downloads for coin hoard data from ancient Sicily: for Greek coin hoards from http://coinhoards.org/pages/about (accessed 06.09.2023) and for Roman coin hoard data from http://numismatics.org/chrr/pages/faq (accessed 06.09.2023)
Prag, Jonathan
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
SOME ASPECTS OF BASES FOR OCCURRING PROPERTY RIGHTS FOR ANTIQUITIES
The article analyzes the issue of occurring property right for antiquities, views the bases for occurring property right for antiquities. The author investigates and analyzes two bases for acquiring a property right for antiquities by discovering a hoard
R. T. Nurullina
doaj
Early medieval hoard of forging and jewelry tools found at Voloave, Soroca District
Depozitul de unelte meşteşugăreşti aparţinând unui făurar-giuvaiergiu, alcătuit din 19 obiecte din fier şi din bronz, a fost descoperit în împrejurimile localităţii Voloave, r-nul Soroca, în toamna anului 2018.
Ion Tentiuc, Valeriu Bubulici
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

