Results 121 to 130 of about 123,814 (303)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Spartan Daily, October 27, 1986 [PDF]
Volume 87, Issue 42https://scholarworks.sjsu.edu/spartandaily/7499/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Spartan Daily, November 6, 1989 [PDF]
Volume 93, Issue 45https://scholarworks.sjsu.edu/spartandaily/7905/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Brăţări din sârme torsionate şi împletite, lăţite la capete (secolele X–XV)
This paper analyses the torsioned bracelets, and the knitted bracelets, with plaques at the ends. The first part synthesizes the stage of the research in Romania.
Oța, S., Dragotă, A., Rustoiu, G.
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The hoard of coins of 15th-16th centuries from the collection of Local Lore Museum in Vylkove
The article presents a hoard of coins of 15th-16th centuries stored in the collection of Local Lore Museum in Vylkove (Kilia raion, Odesa oblast, Ukraine).
Dmitri Yanov
doaj

