Results 131 to 140 of about 123,608 (302)

Brăţări din sârme torsionate şi împletite, lăţite la capete (secolele X–XV)

open access: yesMateriale și Cercetări Arheologice, 2010
This paper analyses the torsioned bracelets, and the knitted bracelets, with plaques at the ends. The first part synthesizes the stage of the research in Romania.
Oța, S., Dragotă, A., Rustoiu, G.
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The hoard of coins of 15th-16th centuries from the collection of Local Lore Museum in Vylkove

open access: yesTyragetia, 2018
The article presents a hoard of coins of 15th-16th centuries stored in the collection of Local Lore Museum in Vylkove (Kilia raion, Odesa oblast, Ukraine).
Dmitri Yanov
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The Urnfield period Dragomelj I hoard: archaeological and chemical investigations

open access: yesArheološki Vestnik
The hoard with over 86 kg of metal products unearthed in the settlement at Dragomelj is dated to Ha B1 and complements the remains of foundry activities in the nearby settlement at Podgorica.
Peter Turk, David J. Heath, Tea Zuliani
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Bronze Age Raw Material Hoard from Greater Poland: Archaeometallurgical Study Based on Material Research, Thermodynamic Analysis, and Experiments. [PDF]

open access: yesMaterials (Basel), 2023
Garbacz-Klempka A   +6 more
europepmc   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The hoard of early medieval tools and weapons found at Sadova-Călăraşi, the Republic of Moldova

open access: yesTyragetia, 2019
Investigaţiile sistematice şi descoperirile fortuite din ultimele decenii au scos la lumină un număr important de vestigii arheologice din perioada evului mediu timpuriu.
Tentiuc Ion, Bubulici Valeriu
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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