Results 161 to 170 of about 124,289 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Complexity of parental number talk predicts preschoolers' gains in cardinal knowledge. [PDF]

Sci Rep
Geary DC, Simsek E, Gable S, Booker JA, Nugent L, Hoard MK.   +5 more
europepmc   +1 more source

Unlocking the organic residues preserved in the corrosion from the Pewsey Hoard vessels. [PDF]

Sci Rep, 2022
Carvalho LDC, Henry R, McCullagh JSO, Pollard AM.   +3 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

"Falling between the cracks": Investigating the competing challenges experienced by professionals working with people who hoard. [PDF]

PLoS One
Kaminskiy E, Staras C, Brown S, Morein-Zamir S.   +3 more
europepmc   +1 more source

Detection of Macrotroponin in Patients Receiving Treatment for Breast Cancer. [PDF]

CJC Open, 2023
Kavsak PA, Hoard B, Mackett K, Mukherjee SD, Bordeleau L, Ellis PM, Dhesy-Thind S.   +6 more
europepmc   +1 more source

Bronze Hoard from Zalaszabar. New Data on the Study of the Tolnanémedi Horizon – Part 2 [PDF]

, 2013
Honti, Szilvia, Kiss, Viktória
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Development and Validation of Radiographic Measurement Templates for Standardized X-ray Analysis. [PDF]

Cureus
Elnaggar A, Allen D, Abdelnour D, Boutany M, Almaat A, Knapp A, Hoard CJ, Vaidya R.   +7 more
europepmc   +1 more source

The provenance of the raw material and the manufacturing technology of copper artefacts from the Copper Age hoard from Magyaregres, Hungary. [PDF]

PLoS One, 2022
Siklósi Z, Horváth E, Villa IM, Nisi S, Mozgai V, Bajnóczi B, Csippán P, Hornok P, Kiss P.   +8 more
europepmc   +1 more source