Results 191 to 200 of about 12,097 (249)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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SSRN Electronic Journal, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Douglas Gale, Tanju Yorulmazer
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Phenomenology of hoarding—What is hoarded by individuals with hoarding disorder?
Journal of Obsessive-Compulsive and Related Disorders, 2012Abstract Hoarding disorder is an under-recognized yet complex and pervasive psychological problem that dominates an individual's time, living spaces, relationships and safety. Hoarding behaviours have been associated with a number of disorders, including Obsessive-Compulsive Disorder (OCD), but as of yet, there has not been a systematic investigation
Mogan, Christopher +4 more
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The Journal of Clinical Psychiatry, 1998
Hoarding behavior in humans spans a continuum from normal collecting to pathological self-neglect and can be associated with a variety of psychiatric disorders.The authors summarize research in the past 15 years characterizing hoarding behavior in groups of college students, in nonclinical populations of self-named "pack rats," in outpatients treated ...
C L, Damecour, M, Charron
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Hoarding behavior in humans spans a continuum from normal collecting to pathological self-neglect and can be associated with a variety of psychiatric disorders.The authors summarize research in the past 15 years characterizing hoarding behavior in groups of college students, in nonclinical populations of self-named "pack rats," in outpatients treated ...
C L, Damecour, M, Charron
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Journal of Clinical Psychology, 2011
AbstractVarious questionnaires and interviews have been created over the years to assess compulsive hoarding. In this article, we summarize existing measures, offer practice‐friendly suggestions for assessment of hoarding, and address frequent problems in its clinical evaluation.
Randy O, Frost, Veselina, Hristova
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AbstractVarious questionnaires and interviews have been created over the years to assess compulsive hoarding. In this article, we summarize existing measures, offer practice‐friendly suggestions for assessment of hoarding, and address frequent problems in its clinical evaluation.
Randy O, Frost, Veselina, Hristova
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Bulletin of the Menninger Clinic, 2010
Compulsive hoarding is a chronic and debilitating condition that represents a significant public health concern. Hoarding is characterized by four key elements: difficulty discarding, excessive acquiring, clutter, and distress and impairment due to hoarding.
Christina M, Gilliam, David F, Tolin
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Compulsive hoarding is a chronic and debilitating condition that represents a significant public health concern. Hoarding is characterized by four key elements: difficulty discarding, excessive acquiring, clutter, and distress and impairment due to hoarding.
Christina M, Gilliam, David F, Tolin
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Communications of the ACM, 2016
Committing to commits, and the beauty of summarizing graphs.
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Committing to commits, and the beauty of summarizing graphs.
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Behaviour Research and Therapy, 1993
Three studies of nonfood hoarding are reported. Findings support the reliability and validity of a Hoarding Scale. Furthermore, the findings indicate a number of features of hoarding behavior. Hoarding was associated with indecisiveness, perfectionism (especially maladaptive evaluative concern) and obsessive compulsive symptoms among college students ...
R O, Frost, R C, Gross
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Three studies of nonfood hoarding are reported. Findings support the reliability and validity of a Hoarding Scale. Furthermore, the findings indicate a number of features of hoarding behavior. Hoarding was associated with indecisiveness, perfectionism (especially maladaptive evaluative concern) and obsessive compulsive symptoms among college students ...
R O, Frost, R C, Gross
openaire +2 more sources