Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Cost-utility Analysis of R-CHOP vs CHOP in Patients with Non-Hodgkin's Lymphoma: A Systematic Review. [PDF]
Cadag CFT +3 more
europepmc +1 more source
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley +15 more
wiley +1 more source
Establishment and validation of a clinical threshold criteria for choosing PET imaging tracers for indolent non-Hodgkin's lymphoma. [PDF]
Yu X +7 more
europepmc +1 more source
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
wiley +1 more source
The Utility of IgG4/IgG Ratio in the Diagnosis of Multicentric Castleman Disease: A Case Report of HHV8+ Castleman Disease in a Patient with Classical Hodgkin's Lymphoma. [PDF]
Hagele A +6 more
europepmc +1 more source
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec +36 more
wiley +1 more source
A Rare Presentation of 17α-Hydroxylase/17,20-Lyase Deficiency in a Patient with Non-Hodgkin’s Lymphoma: A Case Report [PDF]
Tekkeli N +5 more
europepmc +1 more source
The Architecture of Consolidation: Nests of Corporate Control in the Agrochemical Network
ABSTRACT Research on agricultural consolidation tends to equate corporate control with the dominance of a few large firms. We take an alternative approach that examines control through the explosive growth of legally distinct firms that fragment accountability. Using a new global dataset of 6982 entities linked to BASF, Bayer, Corteva, Dow, DuPont, FMC,
Loka Ashwood +5 more
wiley +1 more source
Increasing incidence and prevalence of Hodgkin's lymphoma in Finland: a population-based registry study. [PDF]
Antikainen T +9 more
europepmc +1 more source

