Results 221 to 230 of about 77,535 (306)

The cardiac pacemakers: A paradigm of robustness in evolutionary biology

The Journal of Physiology, EarlyView.
Abstract figure legend Functional networks in living systems are formed by many thousands of gene products. In association with those networks, several genes (four in this diagram) may be sufficient, each on its own, to ensure that the function occurs. Any one of these may be removed or blocked while leaving the others to continue functioning.
Denis Noble
wiley   +1 more source

Anthracyclines effect on mitochondrial function and biogenesis in normal blood cells of hodgkin lymphoma patients. [PDF]

Sci Rep
Sambuceti G, Coco S, Cossu V, Carta S, Lanfranchi F, Ghiggi C, Ceresa D, Pana K, Colombo M, Marconi S, Ghelardoni M, Losacco S, Vitale F, Chiesa S, Orengo AM, Bauckneht M, Angelucci E, Marini C.   +17 more
europepmc   +1 more source

Mixed Lineage Leukemia 5 (MLL5) identified as disease contributing gene by single cell transcriptome analysis of classical pediatric and adult Hodgkin lymphoma

, 2015
David Johann Kirchberger
openalex   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

A peculiar case of primary lymphoma of pancreas: A rare presentation of Hodgkin lymphoma. [PDF]

Oncoscience
Mohiuddin O, Aibani R, Lalani A, Shabbir F, Aibani A, Sharma V.   +5 more
europepmc   +1 more source

Structure mirroring function: What's the ‘matter’ with the funny current?

The Journal of Physiology, EarlyView.
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley   +1 more source

Robust Multimodal Deep Learning for Lymphoma Subtype Classification Using ¹⁸F-FDG PET Maximum Intensity Projection Images and Clinical Data: A Multi-Center Study. [PDF]

Cancers (Basel)
Kim S, Park JH, Kim CH, You S, Choi JS, Chang JW, Jo IY, Lee BJ, Park IS, Kim HS, Park YJ, Heo J.   +11 more
europepmc   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

The Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo, Zachary D. Long, Arie O. Verkerk, Jose M. Ferrero, T. Alexander Quinn, Jose F. Rodriguez Matas   +5 more
wiley   +1 more source

Early-stage Hodgkin lymphoma in Cape Town, South Africa: prognostic risk factors at diagnosis and treatment outcomes. [PDF]

BMC Cancer
Dawood S, McMillan B, Brown K, Oosthuizen J, Richardson D, Simba K, Andera LF, Opie J, Antel K, More S, Allie A, Mohamed Z, Verburgh E.   +12 more
europepmc   +1 more source