Results 21 to 30 of about 75,394 (146)

Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease

Cell Reports
Summary: The brain is spatially organized and contains unique cell types, each performing diverse functions and exhibiting differential susceptibility to neurodegeneration.
Peter Kilfeather, Jia Hui Khoo, Katherina Wagner, Han Liang, Maria Claudia Caiazza, Yanru An, Xingju Zhang, Xiaoyan Chen, Natalie Connor-Robson, Zhouchun Shang, Richard Wade-Martins   +10 more
doaj   +1 more source

Epstein-Barr Virus Promotes Tumorigenicity and Worsens Hodgkin Lymphoma Prognosis by Activating JAK/STAT and NF-κB Signaling Pathways [PDF]

Iranian Journal of Medical Sciences
Background: Epstein-Barr virus (EBV) is detected in 40% of patients with Hodgkin lymphoma (HL). During latency, EBV induces epigenetic alterations to the host genome and decreases the expression of pro-apoptotic proteins.
Mohamed Ali Alabiad, Warda M. M. Said, Rema H Faraj Saad, Rawda Balata, Asmaa A. Mahmoud, Elsayed Anany Metwally, Amany Mohamed Shalaby, Walaa Samy, Ahmed M. Yehia, Amar Ibrahim Omar Yahia, Mohammed Alorini, Doaa I. Abdelrahman   +11 more
doaj   +1 more source

Alterations of Spermatozoa Proteomic Profile in Men with Hodgkin’s Disease Prior to Cancer Therapy

The World Journal of Men's Health, 2020
Purpose: Hodgkin’s disease (HD) is a type of cancer affecting men in the reproductive age with potential consequences on their fertility status. This study aims to analyze sperm parameters, alterations in proteomic profiles and validate selected protein
Ana D. Martins, Ashok Agarwal, Saradha Baskaran, Peter Natesan Pushparaj, Gulfam Ahmad, Manesh Kumar Panner Selvam   +5 more
doaj   +1 more source

Hodgkin transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma [PDF]

Vojnosanitetski Pregled
Introduction. In rare cases, chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma may transform into Hodgkin lymphoma, with about a hundred cases reported in the literature so far.
Vučić Miodrag, Lilić Božidar, Stojnev Slavica, Krstić Miljan   +3 more
doaj   +1 more source

A case study evaluating deep inspiration breath‐hold and intensity‐modulated radiotherapy to minimise long‐term toxicity in a young patient with bulky mediastinal Hodgkin lymphoma

Journal of Medical Radiation Sciences, 2017
Radiotherapy plays an important role in the treatment of early‐stage Hodgkin lymphoma, but late toxicities such as cardiovascular disease and second malignancy are a major concern.
Jonathan M. Tomaszewski, Sarah Crook, Kenneth Wan, Lucille Scott, Farshad Foroudi   +4 more
doaj   +1 more source

HODGKIN DISEASE IN CHILDREN

The Iraqi Journal of Medical Sciences, 2018
Background: Hodgkin lymphoma (HL) is a malignant process involving the lympho-reticular system that accounts for 6% of childhood cancers. Infectious agents may be involved, such as human herpes virus 6, cytomegalovirus, and Epstein-Barr virus ...
Sawsan Abbas, Ruaa Ali
doaj   +1 more source

C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9

Nature Communications, 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron loss, with additional pathophysiological involvement of non-neuronal cells such as microglia.
Björn F. Vahsen, Sumedha Nalluru, Georgia R. Morgan, Lucy Farrimond, Emily Carroll, Yinyan Xu, Kaitlyn M. L. Cramb, Benazir Amein, Jakub Scaber, Antigoni Katsikoudi, Ana Candalija, Mireia Carcolé, Ruxandra Dafinca, Adrian M. Isaacs, Richard Wade-Martins, Elizabeth Gray, Martin R. Turner, Sally A. Cowley, Kevin Talbot   +18 more
doaj   +1 more source

Rapid development of HPV-mediated oropharyngeal squamous cell carcinoma in the setting of immune suppression following autologous stem cell transplantation for Hodgkin lymphoma

Human Pathology: Case Reports, 2017
The patient is a 61-year-old male with a diagnosis of relapse classical Hodgkin lymphoma, treated with ABVD, ICE, and achieved remission. He underwent autologous stem cell transplantation and 3 months later found to have a PET-positive neck node ...
Joo Y. Song, Ellie Maghami, Huiqing Wu, Young S. Kim, Dennis D. Weisenburger, Alexandra Levine, Auayporn Nademanee   +6 more
doaj   +1 more source

Epidemiology of Non-Hodgkin Lymphomas in the 20th and at the beginning of the 21st century

Patologìâ, 2014
Aim: to study the dynamics of incidence, mortality, survival of patients with non-Hodgkin lymphomas in the world, Ukraine and Zaporizhzhya region in the 20th and at the beginning of the 21st century.
A. I. Shevchenko, А. M. Sidorenko, E. R. Krohmalnaya   +2 more
doaj   +1 more source

Hodgkin’s lymphoma in adults – diagnosis and treatment

Family Medicine & Primary Care Review
Hodgkin’s lymphoma (HL) is a malignant disease of the lymphatic system with two peaks of incidence. Often one of the first symptoms of the disease is non-painful enlargement of the lymph nodes.
Anna Gruszczyńska, Krzysztof Kowalik, Dagmara Jabłońska, Katarzyna Hetman, Andrzej Modrzejewski   +4 more
doaj   +1 more source