Results 81 to 90 of about 9,263,948 (394)

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Expression of Cyclooxygenase 2 and p-53 and their Relation with 5 Years Survival in Hodgkin\'s Lymphoma

پزشکی بالینی ابن سینا, 2012
Introduction & Objective: Hodgkin lymphoma accounts for about 1% of all cancers. Cyclooxygenase 2 (COX2) is a cytoplasmic enzyme. Oncogene, and growth factor induce over expression of COX2. COX2 is apoptotic inhibitor.
Effat Abdoli, Alireza Rastgoo Haghi, Saadat Torabian   +2 more
doaj  

Hodgkin's disease and age* [PDF]

European Journal of Haematology, 1989
506 unselected, previously untreated patients with Hodgkin's disease were treated at the Finsen Institute between 1969 and 1983. The prognostic significance of age, sex, stage, systemic symptoms, histologic subtype, number of involved nodal regions, total tumour burden (peripheral + intrathoracic nodal tumour burden, intraabdominal nodal tumour burden,
Specht, L., Nissen, N.I.
openaire   +3 more sources

Rapid onset of hypercalcemia from high-grade lymphoma in the setting of HIV-related immune reconstitution inflammatory syndrome. [PDF]

, 2019
Hypercalcemia in HIV patients has been previously reported, but 1,25-(OH)2 vitamin D-mediated hypercalcemia, due to increased activity of extrarenal 1-alpha hydroxylase, is rarely described with HIV-related infections or malignancies.
Bikle, Daniel, Kim, Sarah, Kim, Stephanie J, Peluso, Michael J, Shoback, Dolores, Wang, Yongmei   +5 more
core  

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, EarlyView.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source

Hodgkin’s lymphoma in adults – diagnosis and treatment

Family Medicine & Primary Care Review
Hodgkin’s lymphoma (HL) is a malignant disease of the lymphatic system with two peaks of incidence. Often one of the first symptoms of the disease is non-painful enlargement of the lymph nodes.
Anna Gruszczyńska, Krzysztof Kowalik, Dagmara Jabłońska, Katarzyna Hetman, Andrzej Modrzejewski   +4 more
doaj   +1 more source

Hodgkin Lymphoma and Castleman Disease: When One Blood Disease Can Hide Another

Case Reports in Hematology, 2017
We describe a rare case of Castleman disease associated de novo with Hodgkin lymphoma. The incidence of Castleman disease is rare; only a few studies have described it in de novo association with Hodgkin lymphoma. The patient described here complained of
L. Filliatre-Clement, H. Busby-Venner, C. Moulin, G. Roth-Guepin, A. Perrot   +4 more
doaj   +1 more source

Different faces of cutaneous Hodgkin′s disease

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2014
Hodgkin′s disease with skin involvement is a rare entity with a reported incidence of 0.5-3.5%. Various routes of skin involvement may include retrograde lymphatic spread, direct extension from underlying nodes, or hematogenous spread.
Shikha Goyal, Ahitagni Biswas, Tarun Puri, Ruchika Gupta, Sandeep Muzumder, Pramod Kumar Julka   +5 more
doaj   +1 more source