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Hodgkin lymphoma: A review and update on recent progress

open access: yesCa-A Cancer Journal for Clinicians, 2018
Hodgkin lymphoma (HL) is a unique hematopoietic neoplasm characterized by cancerous Reed‐Sternberg cells in an inflammatory background. Patients are commonly diagnosed with HL in their 20s and 30s, and they present with supradiaphragmatic lymphadenopathy,
Satish P Shanbhag, Richard F Ambinder
exaly   +2 more sources

The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpoints

open access: yesHaematologica, 2016
Classical Hodgkin lymphoma is curable in the majority of cases with chemotherapy and/or radiation. However, 15–20% of patients ultimately relapse and succumb to their disease.
Santosha Vardhana, Anas Younes
doaj   +2 more sources

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

open access: yesNature, 2011
Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are the two most common non-Hodgkin lymphomas (NHLs). Here we sequenced tumour and matched normal DNA from 13 DLBCL cases and one FL case to identify genes with mutations in B-cell NHL ...
Ryan D Morin   +2 more
exaly   +2 more sources

Detection and prognostic value of recurrent exportin 1 mutations in tumor and cell-free circulating DNA of patients with classical Hodgkin lymphoma

open access: yesHaematologica, 2016
Classical Hodgkin lymphoma is one of the most common lymphomas and shares clinical and genetic features with primary mediastinal B-cell lymphoma. In this retrospective study, we analyzed the recurrent hotspot mutation of the exportin 1 (XPO1, p.E571K ...
Vincent Camus   +19 more
doaj   +2 more sources

Composite follicular lymphoma and classic Hodgkin lymphoma [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2022
Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic problems, but can also affect treatment plan. We report
Han-Na Kim   +5 more
doaj   +1 more source

EBV Plasma Epstein-Barr Virus (EBV) DNA as a Biomarker for Diagnosis of EBV-positive Hodgkin Lymphoma in Syria

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: Epstein Barr Virus - positive Hodgkin lymphoma is defined by the presence of Epstein-Barr virus (EBV) in tumor cells. EBV plays an important role in the development and prognosis of Hodgkin's lymphoma.
Rana Habeeb   +2 more
doaj   +1 more source

Incidence, mortality, risk factors, and trends for Hodgkin lymphoma: a global data analysis

open access: yesJournal of Hematology & Oncology, 2022
Background Hodgkin lymphoma is a lymphatic malignancy commonly found in cervical lymph nodes. This study evaluated the worldwide incidence, mortality, associated risk factors, and temporal trends of Hodgkin lymphoma by sex, age, and country.
Junjie Huang   +9 more
semanticscholar   +1 more source

Hodgkin Lymphoma Cell Lines and Tissues Express mGluR5: A Potential Link to Ophelia Syndrome and Paraneoplastic Neurological Disease

open access: yesCells, 2023
Ophelia syndrome is characterized by the coincidence of severe neuropsychiatric symptoms, classical Hodgkin lymphoma, and the presence of antibodies to the metabotropic glutamate 5 receptor (mGluR5).
Sofia Schnell   +8 more
doaj   +1 more source

Molecular biology of Hodgkin lymphoma

open access: yesLeukemia, 2021
Classical Hodgkin lymphoma (cHL) is unique among lymphoid malignancies in several key biological features. (i) The Hodgkin and Reed-Sternberg (HRS) tumor cells are rare among an extensive and complex microenvironment.
M. Weniger, R. Küppers
semanticscholar   +1 more source

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