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Hodgkin lymphoma: A review and update on recent progress
Hodgkin lymphoma (HL) is a unique hematopoietic neoplasm characterized by cancerous Reed‐Sternberg cells in an inflammatory background. Patients are commonly diagnosed with HL in their 20s and 30s, and they present with supradiaphragmatic lymphadenopathy,
Satish P Shanbhag, Richard F Ambinder
exaly +2 more sources
The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpoints
Classical Hodgkin lymphoma is curable in the majority of cases with chemotherapy and/or radiation. However, 15–20% of patients ultimately relapse and succumb to their disease.
Santosha Vardhana, Anas Younes
doaj +2 more sources
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are the two most common non-Hodgkin lymphomas (NHLs). Here we sequenced tumour and matched normal DNA from 13 DLBCL cases and one FL case to identify genes with mutations in B-cell NHL ...
Ryan D Morin +2 more
exaly +2 more sources
Classical Hodgkin lymphoma is one of the most common lymphomas and shares clinical and genetic features with primary mediastinal B-cell lymphoma. In this retrospective study, we analyzed the recurrent hotspot mutation of the exportin 1 (XPO1, p.E571K ...
Vincent Camus +19 more
doaj +2 more sources
Composite follicular lymphoma and classic Hodgkin lymphoma [PDF]
Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic problems, but can also affect treatment plan. We report
Han-Na Kim +5 more
doaj +1 more source
Introduction: Epstein Barr Virus - positive Hodgkin lymphoma is defined by the presence of Epstein-Barr virus (EBV) in tumor cells. EBV plays an important role in the development and prognosis of Hodgkin's lymphoma.
Rana Habeeb +2 more
doaj +1 more source
Incidence, mortality, risk factors, and trends for Hodgkin lymphoma: a global data analysis
Background Hodgkin lymphoma is a lymphatic malignancy commonly found in cervical lymph nodes. This study evaluated the worldwide incidence, mortality, associated risk factors, and temporal trends of Hodgkin lymphoma by sex, age, and country.
Junjie Huang +9 more
semanticscholar +1 more source
Ophelia syndrome is characterized by the coincidence of severe neuropsychiatric symptoms, classical Hodgkin lymphoma, and the presence of antibodies to the metabotropic glutamate 5 receptor (mGluR5).
Sofia Schnell +8 more
doaj +1 more source
Molecular biology of Hodgkin lymphoma
Classical Hodgkin lymphoma (cHL) is unique among lymphoid malignancies in several key biological features. (i) The Hodgkin and Reed-Sternberg (HRS) tumor cells are rare among an extensive and complex microenvironment.
M. Weniger, R. Küppers
semanticscholar +1 more source

