Results 121 to 130 of about 564,426 (377)

Frequent mutation of histone modifying genes in non-Hodgkin lymphoma

Nature, 2011
Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are the two most common non-Hodgkin lymphomas (NHLs). Here we sequenced tumour and matched normal DNA from 13 DLBCL cases and one FL case to identify genes with mutations in B-cell NHL ...
Ryan D. Morin, María Méndez-Lago, A. Mungall, R. Goya, K. Mungall, R. Corbett, N. Johnson, T. Severson, Readman Chiu, M. Field, S. Jackman, M. Krzywinski, D. Scott, Diane L. Trinh, Jessica Tamura-Wells, Sa Li, M. Firme, S. Rogic, M. Griffith, Susanna Y. Chan, Oleksandr Yakovenko, Irmtraud M. Meyer, E. Zhao, D. Smailus, M. Moksa, S. Chittaranjan, L. Rimsza, A. Brooks-Wilson, J. Spinelli, S. Ben-Neriah, B. Meissner, B. Woolcock, M. Boyle, H. McDonald, Angela Tam, Yongjun Zhao, Allen D. Delaney, Thomas Zeng, Kane Tse, Y. Butterfield, I. Birol, R. Holt, J. Schein, D. Horsman, Richard A. Moore, Steven J. M. Jones, J. Connors, M. Hirst, R. Gascoyne, M. Marra   +49 more
semanticscholar   +1 more source

Global Burden of Disease Due to High Body Mass Index and Projections to 2040: A Study Based on the Global Burden of Disease Study 2019

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background The prevalence of high body mass index (BMI) contributes to an increased risk of various diseases. This study aimed to identify global disease burden trends associated with high BMI from 1990 to 2019 and forecasts up to 2040. Methods Using data from the global burden of disease (GBD) 2019 study, we analysed the number and ratio of ...
Eun‐Ji Kim, Yoonseo Park, Sewon Park, Mihajlo Jakovljevic, Munjae Lee   +4 more
wiley   +1 more source

Clinicopathological features of extranodal lymphomas: Kuwait experience [PDF]

, 2004
A total of 935 patients with extranodal non-Hodgkin lymphoma (NHL) diagnosed in the period between January 1985 and December 2000 in Kuwait Cancer Center, serving the whole population of Kuwait, were used to describe the clinicopathological and ...
Bamanikar S, D'Amore F, Ducreux M, F. Sinowatz, Freeman C, Gospodarowicz MK, H. Amanguno, H. Baker, Hauke RJ, J.P. Madda, L. Temmim, Longo DL, Neugut AI, Penn I, Shome DK, Stiller CA, Weisenburger DD, Zeeb H   +17 more
core   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Possible role of GADD45γ methylation in diffuse large B-cell Lymphoma: Does it affect the progression and tissue involvement? [PDF]

, 2015
Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features.
Barış, İkbal Cansu, Bağcı, Gülseren, Can, Özge, Caner, Vildan, Doğu, Mehmet Hilmi, Hacıoğlu, Sibel, Keskin, Ali, Sarı, İsmail, Tepeli, Emre, Türk, Nilay Şen, Çetin, Ozan   +10 more
core   +2 more sources

Hodgkin’s Lymphoma [PDF]

, 2010
Epidemiology Incidence/mortality in the US for 2008 is 8,220/1,350. Males slightly greater than females (1.1:1). Bimodal peak: ages 25–30 and >55. First-degree relatives of patients have fivefold increase in risk for Hodgkin’s disease. Associated with Epstein–Barr virus, which is associated with mixed cellularity subtype.
Naomi R. Schechter, Stephen L. Shiao, Hans T. Chung   +2 more
openaire   +1 more source

Results of a trial of PET-directed therapy for early-stage Hodgkin's lymphoma.

New England Journal of Medicine, 2015
BACKGROUND It is unclear whether patients with early-stage Hodgkin's lymphoma and negative findings on positron-emission tomography (PET) after three cycles of chemotherapy with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) require ...
J. Radford, T. Illidge, N. Counsell, B. Hancock, R. Pettengell, P. Johnson, J. Wimperis, D. Culligan, B. Popova, Paul Smith, A. McMillan, A. Brownell, A. Kruger, A. Lister, P. Hoskin, M. O'Doherty, S. Barrington   +16 more
semanticscholar   +1 more source

Histologically verified penile lichen sclerosus—Incidence in Denmark over 26 years and long‐term risk of penile and non‐penile cancer

International Journal of Cancer, EarlyView.
What's New? About half of penile squamous cell carcinomas are causally associated with inflammatory conditions such as lichen sclerosus (LSc), but few large‐scale studies have assessed the risk of penile cancer in men with LSc. Here, the authors conducted a large nationwide study in Denmark to estimate the risk of penile and non‐penile cancer in men ...
Marianne Gardar Stærk, Emma L. Kaderly Rasmussen, Charlotte Gerd Hannibal, Rasmus Hertzum‐Larsen, Louise Baandrup, Susanne K. Kjær   +5 more
wiley   +1 more source

Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma.

New England Journal of Medicine, 1995
BACKGROUND High-dose chemotherapy followed by autologous bone marrow transplantation is a therapeutic option for patients with chemotherapy-sensitive non-Hodgkin's lymphoma who have relapses.
T. Philip, C. Guglielmi, A. Hagenbeek, Renier Somers, H. van der Lelie, D. Bron, P. Sonneveld, C. Gisselbrecht, J. Cahn, J. Harousseau, B. Coiffier, P. Biron, F. Mandelli, F. Chauvin   +13 more
semanticscholar   +1 more source

Cancer incidence in people with HIV in Italy: Comparison of the ICONA COHORT with general population data

International Journal of Cancer, EarlyView.
What's New? Immune suppression induced by HIV infection significantly increases the risk of certain cancers among people with HIV (PWH). In the present study, the authors investigated cancer incidence among HIV‐infected individuals in Italy using data from the Italian Cohort Naïve Antiretrovirals. Comparison with the corresponding general population in
Pierluca Piselli, Alessandro Tavelli, Claudia Cimaglia, Camilla Muccini, Alessandra Bandera, Giulia C. Marchetti, Carlo Torti, Valentina Mazzotta, Luca Pipitò, Alessandro Caioli, Enrico Girardi, Andrea Antinori, Diego Serraino, Antonella d'Arminio Monforte, Antonella Cingolani, Icona Foundation Study Group, A d'Arminio Monforte, A Antinori, S Antinori, A Castagna, R Cauda, G Di Perri, E Girardi, R Iardino, A Lazzarin, GC Marchetti, C Mussini, E Quiros‐Roldan, L Sarmati, B Suligoi, F von Schloesser, P Viale, A d'Arminio Monforte, A Antinori, A Castagna, F Ceccherini‐Silberstein, A Cingolani, A Cozzi‐Lepri, A Di Biagio, E Girardi, A Gori, S Lo Caputo, G Marchetti, F Maggiolo, C Mussini, M Puoti, CF Perno, C Torti, A Antinori, A Bandera, S Bonora, A Calcagno, D Canetti, A Castagna, F Ceccherini‐Silberstein, A Cervo, A Cingolani, P Cinque, A Cozzi‐Lepri, A d'Arminio Monforte, A Di Biagio, R Gagliardini, A Giacomelli, E Girardi, N Gianotti, A Gori, G Guaraldi, S Lanini, G Lapadula, M Lichtner, A Lai, S Lo Caputo, G Madeddu, F Maggiolo, V Malagnino, G Marchetti, A Mondi, V Mazzotta, C Mussini, S Nozza, CF Perno, S Piconi, C Pinnetti, M Puoti, E Quiros Roldan, R Rossotti, S Rusconi, MM Santoro, A Saracino, L Sarmati, V Spagnuolo, N Squillace, V Svicher, L Taramasso, C Torti, A Vergori, A Cozzi‐Lepri, S De Benedittis, I Fanti, M Giotta, C Marelli, A Rodano, A Tavelli, M Cernuschi, L Cosmaro, A Perziano, V Calvino, D Russo, M Farinella, N Policek, VL Del Negro, M Augello, S Carrara, S Graziano, G Prota, S Truffa, D Vincenti, R Rovito, M Sgarlata, Italy A Giacometti, A Costantini, V Barocci, A Saracino, C Santoro, E Milano, L Comi, C Suardi, P Viale, L Badia, S Cretella, EM Erne, A Pieri, E Quiros Roldan, E Focà, B Menzaghi, C Abeli, L Chessa, F Pes, P Maggi, L Alessio, G Nunnari, BM Celesia, J Vecchiet, K Falasca, A Pan, S Dal Zoppo, D Segala, F Bartalesi, A Bartoloni, B Borchi, C Costa, S Lo Caputo, S Ferrara, M Bassetti, E Pontali, S Blanchi, N Bobbio, C. Del Borgo, R. Marocco, G. Mancarella, S Piconi, C Molteni, S Rusconi, G Canavesi, G Pellicanò, G Marchetti, S Antinori, A Gori, M Puoti, A Castagna, A Bandera, V Bono, MV Cossu, A Giacomelli, R Lolatto, MC Moioli, L Pezzati, S Diotallevi, C Tincati, C Mussini, M Menozzi, P Bonfanti, G Lapadula, V Sangiovanni, I Gentile, V Esposito, N Coppola, FM Fusco, G Di Filippo, V Rizzo, N Sangiovanni, S Martini, AM Cattelan, D Leoni, A Cascio, M Trizzino, D Francisci, E Schiaroli, G Parruti, F Sozio, D Messeri, SI Bonelli, C Lazzaretti, R Corsini, A Antinori, R Cauda, C Mastroianni, L Sarmati, A Latini, A Cingolani, I Mastrorosa, S Lamonica, M Capozzi, M Camici, I Mezzaroma, M Rivano Capparuccia, G Iaiani, C Stingone, L Gianserra, J Paulicelli, MM Plazzi, G d'Ettore, M Fusto, M Lichtner, I Coledan, G Madeddu, A De Vito, M Fabbiani, F Montagnani, A Franco, R Fontana Del Vecchio, D Francisci, C Di Giuli, GC Orofino, G Calleri, G Di Perri, S Bonora, G Accardo, C Tascini, A Londero, G Battagin, S Nicolè, G Starnini, S Dell'Isola   +243 more
wiley   +1 more source