A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line [PDF]
, 2019 The circadian clock regulates key cellular processes and its dysregulation is associated to several pathologies including cancer. Although the transcriptional regulation of gene expression by the clock machinery is well described, the role of the clock ...
Abreu, Mónica +4 more
core +1 more source
Relation between Coronary Artery Calcium Score and Cardiovascular Events in Hodgkin Lymphoma Survivors: A Cross-Sectional Matched Cohort Study [PDF]
, 2023 E Polomski +9 more
openalex +1 more source
Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders
Advanced Science, EarlyView.This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin +8 more
wiley +1 more source
Human Immunodeficiency Virus Related Non-Hodgkin’s Lymphoma
Blood and Lymphatic Cancer: Targets and Therapy, 2023 Tesfaye Gessese,1 Fikir Asrie,2 Zewudu Mulatie1 1Department of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Hematology and Immunohematology, School of Biomedical and Laboratory ...
Gessese T, Asrie F, Mulatie Z
doaj
Family members dealing with childhood cancer : a study on the role of family functioning and cancer appraisal [PDF]
, 2019 Objectives: Childhood cancer is a life-threatening disease that poses significant challenges to the life of the diagnosed child and his/her family members.
Cosyns, Veerle +7 more
core +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Association of Disease Location and Treatment With Survival in Diffuse Large B-Cell Lymphoma of the Eye and Ocular Adnexal Region. [PDF]
, 2017 Importance: Primary diffuse large B-cell lymphoma (DLBCL) of the ocular region is rare, and the utility of surgery and radiation therapy remains unresolved.
Ahmed, Aseef H H. +2 more
core +2 more sources
CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas
American Journal of Hematology, EarlyView.ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley +1 more source
Anti-programmed cell death protein-1/ligand-1 therapy in different cancers. [PDF]
, 2015 Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby promoting immune responses against several cancer types ...
Homet Moreno, B, Ribas, A
core +2 more sources
Metabolism‐Regulating Nanomedicines for Cancer Therapy
Advanced NanoBiomed Research, EarlyView.This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source