Results 141 to 150 of about 33,262 (281)

Smoking Cessation, Weight Gain, and the Trajectory of Estimated Risk of Coronary Heart Disease: 8-Year Follow-up From a Prospective Cohort Study. [PDF]

Nicotine Tob Res, 2021
Chen S, Kawasaki Y, Hu H, Kuwahara K, Yamamoto M, Uehara A, Honda T, Yamamoto S, Nakagawa T, Miyamoto T, Okazaki H, Hori A, Shimizu M, Murakami T, Kochi T, Eguchi M, Imai T, Nishihara A, Tomita K, Akter S, Kabe I, Mizoue T, Dohi S.   +22 more
europepmc   +1 more source

Policy Barriers to Ainu Language Revitalization in Japan: When Globalization Means English [PDF]

, 2017
For over a century the Ainu language has been threatened with disappearance as a result of language policies imposed by the Japanese following colonization of Ainu Mosir (now known as Hokkaidō), the Indigenous Ainu homeland.
Hanks, David H
core   +1 more source

Decreased renal function predicts severe cytokine release syndrome after CAR‐T‐cell therapy for large B‐cell lymphoma

British Journal of Haematology, EarlyView.
Summary Cytokine release syndrome (CRS) remains a major toxicity of chimeric antigen receptor (CAR) T‐cell therapy in large B‐cell lymphoma (LBCL), and robust pre‐infusion predictors are needed for risk‐adapted management. We retrospectively analysed LBCL patients in the Japanese nationwide registry who underwent CD19 CAR‐T‐cell therapy between 2019 ...
Yasuyuki Arai, Tomoyasu Jo, Takayuki Sato, Masatoshi Sakurai, Daisuke Kaji, Toshio Kitawaki, Kazuyuki Shimada, Tatsu Shimoyama, Satoshi Yoshihara, Shinichi Makita, Nobuharu Fujii, Go Yamamoto, Keisuke Kataoka, Emiko Sakaida, Hideki Goto, Yasuhiro Nakashima, Akiyo Yoshida, Yoshihiro Umezawa, Haryoon Kim, Motohiro Kato, Yoshiko Atsuta, Koji Kato   +21 more
wiley   +1 more source

Stress drops of intermediate-depth intraslab earthquakes beneath Tohoku, northern Japan

Earth, Planets and Space
We calculated stress drops for 2875 small intraslab earthquakes at intermediate depths beneath Tohoku, Japan. We applied an S-coda-wave spectral ratio method to almost 900,000 event pairs.
Saeko Kita, Takahiro Shiina, Heidi Houston, Katsuhiko Shiomi   +3 more
doaj   +1 more source

Impact of CD34+ cell dose on outcomes of related allogeneic PBSCT in adult AML patients

British Journal of Haematology, EarlyView.
Summary CD34+ cell dose is believed to impact the outcomes of allogeneic peripheral blood stem cell transplantation (PBSCT), yet the optimal dose remains unclear. We retrospectively reviewed 2407 adult patients with acute myeloid leukaemia who underwent their first related PBSCT between 2000 and 2019.
Yusuke Toda, Tomoyasu Jo, Yasuyuki Arai, Kaito Harada, Masamitsu Yanada, Takahiro Fukuda, Satoshi Yoshihara, Noriko Doki, Naoyuki Uchida, Yasuo Mori, Yuta Hasegawa, Yukio Kondo, Toshiro Kawakita, Tetsuya Eto, Tetsuya Nishida, Masatsugu Tanaka, Makoto Onizuka, Katsuhiro Shono, Masayuki Hino, Tatsuo Ichinohe, Yoshiko Atsuta, Takaaki Konuma   +21 more
wiley   +1 more source

Two Circumpolar Ground Beetle Species (Coleoptera: Carabidae) Were in Hokkaido, Japan, Late in the Last Glacial Period

Quaternary
Fossilized body parts of two cold-adapted ground beetle species, Elaphrus lapponicus and Diacheila polita, were identified from a deposit dated to the Late Glacial period in Hokkaido, Japan.
Shigehiko Shiyake
doaj   +1 more source

Molecular and clinical features of a Japanese medulloblastoma cohort: Subgroup‐specific prognostic stratification using economical/accessible diagnostic methods

Brain Pathology, EarlyView.
This study characterizes the molecular subgroup–specific features of a nationwide Japanese cohort comprising 242 medulloblastomas (MBs). Furthermore, we introduce SEE‐6‐CNA, a simple, cost‐effective, and FFPE‐compatible molecular test that is applicable to routine pathology samples and serves as a surrogate for risk stratification in non‐WNT/non‐SHH ...
Kohichi Go, Asako Katsuma, Ema Yoshioka, Tomoko Shofuda, Kohei Fukuoka, Koichi Ichimura, Yuko Matsushita, Yohei Mineharu, Yasuhide Makino, Takeshi Kawauchi, Atsushi Sasaki, Junko Hirato, Takeshi Inoue, Yoshinori Kodama, Masayuki Mano, Daisuke Kanematsu, Noriyuki Kijima, Naoki Kagawa, Dai Keino, Akitake Mukasa, Tomonari Suzuki, Koji Yoshimoto, Daisuke Kuga, Keishi Horiguchi, Shigeru Yamaguchi, Masayuki Kanamori, Kai Yamasaki, Kenichi Ishibashi, Takuya Akai, Masayoshi Yamaoka, Ryuji Ishizaki, Atsufumi Kawamura, Shigeo Ohba, Joji Ishida, Ryo Ando, Junya Fukai, Tomoru Miwa, Masazumi Fujii, Ai Muroi, Kuniaki Saito, Atsuko Harada, Yasuhiko Hayashi, Masahiro Nonaka, Young‐Soo Park, Yusuke Kobayashi, Tadashi Higuchi, Yosuke Miyairi, Kazuhisa Yoshifuji, Noriyoshi Takebe, Soichi Oya, Kosuke Nakajo, Mitsutoshi Nakada, Yoshiteru Nakano, Mizuki Kambara, Koji Adachi, Kazuhiro Tanaka, Hideo Nakamura, Yukihiko Sonoda, Ryuta Saito, Takafumi Wataya, Kazuhiko Kurozumi, Michael D. Taylor, Yoshitaka Narita, Soichiro Shibui, Hajime Arai, Hiroaki Sakamoto, Isao Date, Motoo Nagane, Ryo Nishikawa, Yoshiki Arakawa, Yonehiro Kanemura   +70 more
wiley   +1 more source

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Plasma Protein Analysis for Biomarker Discovery in Lung Cancer Treated With Atezolizumab Combination Therapy in J‐TAIL‐2

Cancer Science, EarlyView.
BLURB FOR ETOC: The J‐TAIL‐2 study (NCT04501497) evaluated the efficacy and safety of atezolizumab, an anti‐programmed death‐ligand 1, plus chemotherapy in patients with non‐small cell lung cancer (NSCLC) and extensive‐stage small cell lung cancer (ES‐SCLC) in real‐world settings.
Yasushi Goto, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Junichi Shimizu, Eisaku Miyauchi, Hiroshige Yoshioka, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Nobuyuki Katakami, Akira Kisohara, Masafumi Yamaguchi, Hirotaka Kuroki, Masamichi Sugimoto, Hisao Ashimura, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

MAP17 Enhances Chemoresistance and Tumorigenicity of Glioblastoma‐Initiating Cells via the Canonical NF‐кB Pathway

Cancer Science, EarlyView.
MAP 17 is identified as highly expressed in TMZ‐resistant glioblastoma‐initiating cells (GICs). MAP17 enhances GIC proliferation, TMZ resistance, and tumorigenicity through NF‐κB/RELA‐dependent BCL2 upregulation. ABSTRACT Glioblastoma (GBM) is the most common malignant brain tumor in adults.
Shenshen Dou, You Lee Son, Toru Kondo
wiley   +1 more source