Results 111 to 120 of about 1,286,713 (353)
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar +4 more
wiley +1 more source
Silicon Nanowire Mats Enable Advanced Bioelectrical Recordings in Primary DRG Cell Cultures
Advanced Healthcare Materials, EarlyView.SiNW mat‐based MEA (NW_MEA) enables continuous intracellular recordings from neurons in primary rat DRG cell cultures, identifying C‐fiber nociceptors. Supported by an astrocyte feeder layer, SiNW mat promotes DRG neuron and glial cell growth, preserving in vivo‐like cell characteristics and allowing drug‐modulated activity monitoring.
Ivano Lucarini +12 more
wiley +1 more source
A Holistic Approach in Embedded System Development
, 2015 We present pState, a tool for developing "complex" embedded systems by integrating validation into the design process. The goal is to reduce validation time. To this end, qualitative and quantitative properties are specified in system models expressed as
Nokovic, Bojan, Sekerinski, Emil
core +2 more sources
Advanced Healthcare Materials, EarlyView.Designing an engineering material that simultaneously promotes the growth of beneficial biological cells while eliminating harmful bacteria is often challenging. However, this study presents a unique carbon coating by manufacturing design capable of achieving both functions, demonstrating strong potential for various applications, including medical ...
Abdul Wasy Zia +8 more
wiley +1 more source
Holistic, Ethical Leadership for the 21st Century [PDF]
, 2018 The New Oxford American Dictionary (2001) delineates two definitions for a leader: “1) The person who leads or commands a group, organization, or country; a person followed by others.
Barrett, David C.
core +1 more source
An Holistic Approach to Dependability? [PDF]
, 1997 This panel will address the problem of methods for dependability analysis and evaluation of computer system, where the human, hardware and software components are considered by an integrated approach. The state of the art consists of well developed methods in particular domains, but dependability is a total system concept.
Pasquinin, Alberto +3 more
openaire +4 more sources
Recalling Holistic Information for Semantic Segmentation [PDF]
arXiv, 2016 Semantic segmentation requires a detailed labeling of image pixels by object category. Information derived from local image patches is necessary to describe the detailed shape of individual objects. However, this information is ambiguous and can result in noisy labels.
arxiv
Materials, Structure, and Interface of Stretchable Interconnects for Wearable Bioelectronics
Advanced Materials, EarlyView.Stretchable interconnects are one of the fundamental components in achieving robust wearable devices, but their importance is often overlooked. This review highlights their importance and provides insightful information on various materials, configurations, and manufacturing approaches being studied for interconnects.
Yue Li +3 more
wiley +1 more source
LabelBank: Revisiting Global Perspectives for Semantic Segmentation [PDF]
arXiv, 2017 Semantic segmentation requires a detailed labeling of image pixels by object category. Information derived from local image patches is necessary to describe the detailed shape of individual objects. However, this information is ambiguous and can result in noisy labels.
arxiv