Results 211 to 220 of about 775,433 (380)

Holistic Integration of Omics Tools for Precision Nutrition in Health and Disease [PDF]

open access: gold, 2022
Omar Ramos-López   +2 more
openalex   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

open access: yesAdvanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu   +15 more
wiley   +1 more source

Zonated Copper‐Driven Breast Cancer Progression Countered by a Copper‐Depleting Nanoagent for Immune and Metabolic Reprogramming

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen   +16 more
wiley   +1 more source

Service innovation for living well with type 1 Diabetes [PDF]

open access: yes
The UK’s NHS must evolve to embrace the co-production of health outcomes and patient-centred care to shift from the reductive treatment of illness to a holistic promotion of wellness.
Bowen, Simon, Wolstenholme, Dan
core  

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