Results 201 to 210 of about 333,130 (305)

Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers

British Journal of Clinical Pharmacology, EarlyView.
Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard, Diane Merino, Marc Labriffe, Fanny Rocher, Delphine Viard, Laurence Zemori, Thibaud Lavrut, Erik M. Donker, Joost D. Piët, Jean‐Paul Fournier, Milou‐Daniel Drici, Alexandre Destere   +11 more
wiley   +1 more source

Expanding the Data Science Toolkit: Mixed Methods for Improving Causal Inference. [PDF]

Harv Data Sci Rev
Qaragholi N, Stuart EA.
europepmc   +1 more source

Prevalence and impact of prescribing cascades in community‐dwelling adults: Longitudinal analysis of the Irish longitudinal study on ageing (TILDA)

British Journal of Clinical Pharmacology, EarlyView.
Prescribing cascades occur when medication is prescribed to prevent/treat the adverse effects of another medication and may be intentional/unintentional. This study examines the prevalence of nine prescribing cascades (ThinkCascades) in The Irish Longitudinal StuDy on Ageing (TILDA).
Ann Sinéad Doherty, Rose Anne Kenny, Frank Moriarty, Fiona Boland, Barbara Clyne, Tom Fahey, Denis O' Mahony, Emma Wallace   +7 more
wiley   +1 more source

The distribution of power and inclusiveness across deep time. [PDF]

Sci Adv
Feinman GM, Stasavage D, Carballo DM, Barber SB, Green A, Holland-Lulewicz J, Lawrence D, Munson J, Nicholas LM, Fulminante F, Klassen S, Kintigh KW, Douglass J.   +12 more
europepmc   +1 more source

Gescryfte met letteren na elcxs geval Gegraueert en oic dyveerssche ymagyen: Uses of Code-Switching in Dutch and French

, 2017
Catherine Emerson
openalex   +2 more sources

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Motion-based tissue <i>ex vivo</i> (MOTEX) assay to assess proton and X-ray irradiation responses in head and neck squamous cell carcinoma. [PDF]

Clin Transl Radiat Oncol
Pachler KS, Lauwers I, Verkaik NS, Rovituso M, Mast H, Jonker BP, Kremer B, Koppes SA, van den Bosch TPP, Verduijn GM, Petit S, Sørensen BS, van Gent DC, Capala ME.   +13 more
europepmc   +1 more source

Trust first, concerns second: An international vignette study of older adults' preferences towards deprescribing statins

British Journal of Clinical Pharmacology, EarlyView.
Abstract This study investigated the attitudes and beliefs of older adults towards deprescribing statins in Australia, the United Kingdom and the United States, using an online, vignette‐based study. Presented with a hypothetical scenario in which a general practitioner advised stopping simvastatin, participants rated their level of agreement and ...
Sarah E. Vordenberg, Noelia Dulo, Carissa Bonner, Eliza Ferguson, Vincent D. Marshall, Kristie Rebecca Weir   +5 more
wiley   +1 more source

Commercial tobacco endgame themes in the Australian media from 2000 to 2021. [PDF]

Tob Control
Perusco A, Holland A, Maddox R, Morphett K, Heris C, Gartner CE.   +5 more
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source