Results 1 to 10 of about 279 (123)

Molecular Networking-Based Analysis of Cytotoxic Saponins from Sea Cucumber Holothuria atra [PDF]

Marine Drugs, 2019
The saponin composition of a specimen of black sea cucumber, Holothuria atra collected in the Persian Gulf was studied by a combined approach including LC-MS/MS, Molecular Networking, pure compound isolation, and NMR spectroscopy. The saponin composition
Laura Grauso, Afsaneh Yegdaneh, Mohsen Sharifi, Alfonso Mangoni, Behzad Zolfaghari, Virginia Lanzotti   +5 more
doaj   +2 more sources

Fatty Acid-Rich Extract from Holothuria atra for Hyperuricemia via Expressions Modulation of GLUT9a and GLUT9b in Rat Model [PDF]

Molecules, 2023
An edible sea cucumber Holothuria atra has been hypothesized to have medicinal benefits against hyperuricemia owing to its bioactive compounds, including mono- and poly-unsaturated fatty acids. Herein, we aimed to investigate the fatty acids-rich extract
Ikhsan Ikhsan, Rinaldi Idroes, Azharuddin Azharuddin, Rosnani Nasution, Rika Yusnaini, Muhammad Iqhrammullah   +5 more
doaj   +2 more sources

Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra. [PDF]

PLoS ONE, 2015
Lysophospholipids are important signaling molecules in animals and metazoan cells. They are widely distributed among marine invertebrates, where their physiological roles are unknown. Sea cucumbers produce unique lysophospholipids.
Yoshifumi Nishikawa, Ayumi Furukawa, Ikumi Shiga, Yoshikage Muroi, Toshiaki Ishii, Yayoi Hongo, Shunya Takahashi, Tatsuya Sugawara, Hiroyuki Koshino, Masao Ohnishi   +9 more
doaj   +2 more sources

The complete mitochondrial genome of Holothuria atra (Holothuriida: Holothuriidae: Holothuria) and its structural characteristics. [PDF]

PLoS ONE
Sea cucumbers, as typical representatives of deep-sea benthic animals, possess significant scientific and economic importance. This investigation examined the genomic structural characteristics and genetic evolutionary relationships of Holothuria atra ...
Jinjin Wang, Jianlong Ge, Meijie Liao, Bin Li, Xiaojun Rong, Yingeng Wang, Aijun Cui, Xiaodong Bian, Mingliang Sun, Qingyu Zhang   +9 more
doaj   +2 more sources

Individual response in basal metabolism and nutritional composition to asexual reproduction in tropical sea cucumber Holothuria atra [PDF]

PeerJ
Backgroud Asexual reproduction via fission plays a vital role in the survival of the sea cucumber Holothuria atra. However, the energetic and nutritional mechanisms driving its regenerative capacity remain poorly understood. Method Fission was induced in
Haiqing Wang, Yan Zhao, Jingting Xie, Yanchao Chai   +3 more
doaj   +3 more sources

Microencapsulation, Physicochemical Characterization, and Antioxidant, Antibacterial, and Antiplasmodial Activities of Holothuria atra Microcapsule. [PDF]

Scientifica (Cairo)
This study provides the design of a microencapsulation formula, physicochemical characterization, and antioxidant, antibacterial, and antiplasmodial activities of Holothuria atra microcapsules. The ethanolic extract of H. atra was microencapsulated with chitosan (CHI) and sodium tripolyphosphate (Na‐TPP) with various stirring times: 60 minutes (CHI60),
Utami PD, Setianingsih H, Tirto Sari DR.
europepmc   +2 more sources

Integrated In Vitro, In Vivo, and In Silico Evaluation of Antioxidant, Anti-Inflammatory, Analgesic, and Anti-Arthritic Activities of Selected Marine Species [PDF]

Bioengineering
Marine ecosystems represent a largely untapped reservoir of bioactive compounds with significant pharmacological potential. This study aimed to evaluate the therapeutic properties of ethanol extracts from four marine species: Padina australis ...
Md. Jahin Khandakar, Ainun Nahar, Md. Wahidul Alam, Md. Jahirul Islam Mamun, Abu Sayeed Muhammad Sharif, Asef Raj, Md. Enamul Hoque, Israt Sultana Isha, Nafisa Nawsheen, Saika Ahmed, Md Riasat Hasan, Abu Bin Ihsan, Takashi Saito   +12 more
doaj   +2 more sources

Toxicity effects of water extracts of H olothuria atra Jaeger in mice [PDF]

Asian Pacific Journal of Tropical Biomedicine, 2014
Objective: To determine lethal median dose (LD50) and histopathological toxicity of water extract of Holothuria atra (H. atra) in mice. Methods: The behavioral changes, mortality and histopathology examination on liver were assessed in mice 14 d after ...
Ridzwan Bin Hashim, Nurul Alia Azizan, Zaitunnatakin Zamli, Farah Hanis Zulkipli, Nurzafirah Mazlan, Osama Yousef Althunibat   +5 more
doaj   +2 more sources

Hepatorenal protective role of encapsulated Holothuria atra in a mice model of Plasmodium berghei ANKA inoculation [PDF]

Journal of Advanced Veterinary and Animal Research
Objectives: Malaria continues to pose a substantial, widespread health challenge, necessitating innovative therapeutic approaches to combat drug resistance and alleviate organ damage associated with infection.
Prawesty Diah Utami, Herin Setianingsih, Dewi Ratih Tirto Sari   +2 more
doaj   +2 more sources

Untargeted Metabolomics Reveals Seasonal and Tissue-Specific Metabolic Shifts in Holothuria cinerascens. [PDF]

Chem Biodivers
Untargeted metabolic profiling of three body tissues from Holothuria cinerascens in South Africa using 1H‐NMR and UPLC–QTOF–MS revealed distinct tissue‐specific and seasonal metabolic variations, with the body wall and gut/mesentery exhibiting high metabolite diversity.
Upton C, Prinsloo G, Steenkamp P, Okpeku M.   +3 more
europepmc   +2 more sources