Results 121 to 130 of about 56,233 (264)

Genome-Wide Association Studies of Milk Composition Traits in Holstein Cattle Raised in Tropical and Subtropical Conditions. [PDF]

Animals (Basel)
Silva EFP, Gaia RC, Mulim HA, Pinto LFB, Iung LHS, Brito LF, Pedrosa VB.   +6 more
europepmc   +1 more source

Comparative Real‐World Effectiveness of Anti‐TNF, Ustekinumab and Vedolizumab in Crohn's Disease Over 24 Months: A Pooled Analysis From the Prospective UMBRELLA‐IBD Registry in Germany

Alimentary Pharmacology &Therapeutics, EarlyView.
A pooled analysis from the prospective UMBRELLA‐IBD registry in Germany (n = 1567) showed comparative real‐world effectiveness in treatment persistence and clinical remission of anti‐TNF, Ustekinumab and Vedolizumab in Crohn's disease patients over 24 months.
Arne Bokemeyer, Florian Tran, Sandra Plachta‐Danielzik, Elena Gilman, Thomas Wenske, Matthew Gaskins, Stefan Schreiber, Bernd Bokemeyer   +7 more
wiley   +1 more source

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

Recent population history in Swedish cattle breeds. [PDF]

Genet Sel Evol
Adepoju D, Ohlsson JI, Klingström T, Rius-Vilarrasa E, Johansson AM, Johnsson M.   +5 more
europepmc   +1 more source

Learner Advocates: Co‐Designing Disability Awareness in Higher Education

British Journal of Learning Disabilities, EarlyView.
ABSTRACT Background and Aims This study explores the experiences of students with intellectual disabilities participating in a co‐designed, experiential Disability Rights module within the Certificate in Arts, Science and Inclusive Applied Practice programme at Trinity College Dublin.
Des Aston, Vivian Rath, Emma McGrath, Gillian Cronin, Dale O'Neill, Saoirse Keogh, Patricia McCarthy, Angela Mazzocco   +7 more
wiley   +1 more source

Bidirectional regulation of gut microbiota and young ruminant host: implications for intestinal development and mucosal immunity. [PDF]

J Anim Sci Biotechnol
Walelegne M, Junnan M, Hao Y, Feng X, Abebe H, Yang R, Kong L, Tu Y.   +7 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Factors Associated With Parent‐Reported Caries in Preschool Children From the KUNO‐Kids Health Study—Repeated Cross‐Sectional Analysis

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives This questionnaire‐based study aimed to assess parent‐reported caries (PRC) at ages 2–5 years and identify potential influencing factors using an exploratory, repeated cross‐sectional analysis within an ongoing birth‐cohort study.
Áine M. Lennon, Katharina Fluch‐Maier, K.‐A. Hiller, Isabelle Schenke, Nils Gade, W. Buchalla, Susanne Brandstetter, Angela Köninger, Michael Melter, Christian Apfelbacher, Michael Kabesch, KUNO‐Kids Study group, Andreas Ambrosch, Petra A. Arndt, Andrea Baessler, Mark Berneburg, Romuald Brunner, Sara Fill Malfertheiner, André Franke, Stephan Gerling, Iris Heid, Stefanie Heinze, Wolfgang Högler, Sebastian Kerzel, Michael Koller, Michael Leitzmann, Áine Lennon, David Rothfuß, Martin Promm, Bianca Schaub, Stephan Weidinger, Sven Wellmann   +31 more
wiley   +1 more source

Learning to Evaluate Yourself. The Consequences of Institutionalized Understandings of Progression for Young People With Care Experience

Child &Family Social Work, EarlyView.
ABSTRACT This article examines how young people who have been closely involved with child welfare services throughout their upbringing are required to assess and evaluate their life and progress in institutionalized ways. Within Danish child welfare policy and social work practice, progress is institutionally understood as a linear and one‐dimensional ...
Anne‐Kirstine Mølholt, Tea Torbenfeldt Bengtsson   +1 more
wiley   +1 more source

A Scoping Review of Mixed Initiative Visual Analytics in the Automation Renaissance

Computer Graphics Forum, EarlyView.
Abstract Artificial agents are increasingly integrated into data analysis workflows, carrying out tasks that were primarily done by humans. Our research explores how the introduction of automation recalibrates the dynamic between humans and automating technology. To explore this question, we conducted a scoping review encompassing twenty years of mixed‐
Shayan Monadjemi, Yuhan Guo, Kai Xu, Alex Endert, Anamaria Crisan   +4 more
wiley   +1 more source