Results 81 to 90 of about 152,081 (303)
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
El “hombre nuevo” y el Ministerio de Educación y Salud de Río de Janeiro (1930-1945)
Historia y Sociedad, 2022 gestada en el giro del siglo XIX al XX en el Reino Unido, la eugenesia fue trascendiendo sus fronteras de manera inusitada. Su diversidad se hizo particularmente notoria durante la década de 1930, cuando la expansión en Sudamérica dejó entrever precisos
Gustavo Vallejo
doaj
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Pensamiento, acción y realidad
Estudios de Derecho, 1959 Pensamiento, acción y ...
Bernardo Vieira J.
doaj
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Recognition in Hegel’s Real Philosophy of Jena (1805-06)
Miscelánea Comillas, 2017 Hegelian philosophy has been a great influence on contemporary Western thought. The concept of Spirit is relevant to understand ideas like progress and history.
Soledad Escalante Beltrán
doaj
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Comunicación y Hombre is a scientific, interdisciplinary and international journal of communication sciences and humanities. It aims to provide a forum for discussion and the dissemination of original research in disciplines that are directly related to
lucia floridi
core
Escuela Abierta, 2019 Este presente artículo es una reflexión sobre el Hombre en tiempos del postmodernismo y el mundo que le rodea. Mientras que la descripción clásica del hombre toma como ejemplo a Prometeo, la reflexión postmoderna defiende a Narciso como posible paradigma
Julio Oliva Cantero
doaj
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source