Results 101 to 110 of about 1,110,686 (244)

Factores asociados al aumento de infecciones de transmisión sexual en hombres: una revisión integradora

open access: yesEnfermería Global
Objetivo: Analizar la evidencia científica existente sobre los factores asociados a un comportamiento de riesgo en hombres en relación al aumento de infecciones de transmisión sexual (ITS). Método: Revisión integradora mediante búsqueda bibliográfica en
Cristina Lao-López   +2 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Percepciones de la violencia de género en hombres asistentes a cursos de nuevas masculinidades en México. Una observación antropológica crítica

open access: yesEstudios Culturales
Propongo un estudio que tiene como objetivo reflexionar, después de 14 años de experiencia (2011-2025), los impactos en cuanto a la posición frente a la violencia de género, de parte de varones mayores de edad en dos latitudes de México: Tlaxcala y ...
Ángel Christian Luna Alfaro
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Recursos de legitimación en torno a prácticas encubiertas de dominación masculina en la sociedad costarricense. Subterfugios de una hegemonía en declive/Legitimation Resources Around Male Domination Practices in Costa Rican Society. Subterfuges of a Declining Hegemony

open access: yesRevista Costarricense de Psicología, 2019
Español A través de las siguientes líneas, se pretende, con un recorrido por algunos términos y autores característicos de los estudios de hombres y masculinidades, explorar elementos con respecto a manifestaciones y dinámicas de dominación masculina ...
Dennis Redondo
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Corals from the Upper Cretaceous (Maastrichtian) Ocozocoautla Formation, Chiapas, Mexico

open access: yesRevista Mexicana de Ciencias Geológicas, 2018
The coral species from the Upper Cretaceous (Maastrichtian) strata of the Ocozocoautla Formation in Chiapas, Mexico, are identified, described and illustrated for the first time.
Harry F. Filkorn   +3 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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