Results 121 to 130 of about 1,110,686 (244)
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
El sujeto ante la dignidad. Algunos aspectos éticos de las IPS y su posible desarrollo investigador. [PDF]
, 2008 La declaración del 48 con su referencia a la dignidad humana buscaba en su linea principal eliminar la capacidad de discriminación legal entre hombres plenamente humanos y hombres no humanos o subhumanos. El proceso ha tenido un éxito fundamental pero
Serrano, J.M. (José Miguel)
core
Percepción de los hombres ante la aceptación o rechazo de la vasectomía. Cartagena 2013
Duazary, 2014 Title: Perception of men to the acceptance or rejection of the vasectomy. Cartagena 2013ResumenLa vasectomía es un procedimiento complejo que afecta la vida sexual de los hombres.
Shirley Fernández Aragón +4 more
doaj
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
Prevalencia y determinantes del uso de condón en hombres nicaragüenses entre 15-59 años durante 2011-2012 [PDF]
, 2017 Los preservativos son un elemento clave de las estrategias de prevención a la que se pueden optar en diferentes momentos la vida para reducir los riesgos de la exposición sexual al Virus de inmunodeficiencia humana.
Molina Rodríguez, Adriana Raquel
core