Results 41 to 50 of about 462,231 (311)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Relationship between diversification of place of work and organizational commitment

open access: yesAnnals of Business Administrative Science
This study shows that a positive correlation exists between diversification of place of work and organizational commitment. The study compared the working-at-the-office group, working-from-home group, and shared-office-use group using data from an ...
Nobuyuki Inamizu
doaj   +1 more source

Diagnosing Hypertension in Primary Care: A Comparison of Three Methods

open access: yesTurkish Journal of Nephrology, 2019
Objective: The aim of this study was to compare the office and home blood pressure measurements with 24 hours ambulatory blood pressure measurements, and to decide which method could be used for the diagnosis of hypertension in primary care.
Selçuk Mıstık   +4 more
doaj   +1 more source

Response to the Home Office Consultation (2006) on 'Making Sentencing Clearer' [PDF]

open access: yes, 2007
This is the response of Dr Easton and Professor Piper to the Consulation Paper, 'Making Sentencing Clearer' published by the Home Office in 2006. The deadline for responses was 9 January 2007 and a summary of responses will be published on the Home ...
Easton, S, Piper, CD
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Home office és COVID-19 a munkavállalók nézőpontjából

open access: yesTér–Gazdaság–Ember, 2022
A 2020 tavaszán, Magyarországon is megjelent COVID-19 koronavírus járványszerű terjedése, mely az eddigi megszokott, többnyire hagyományos, személyes munkavégzés módját jelentősen átalakította.
Katalin Lipták
doaj  

The Psychological Aspects of Virtual Office at Home for Employees and Employers During The COVID-19 Pandemic

open access: yesJournal of Indonesian Economy and Business, 2022
Introduction/Main Objectives: The COVID-19 pandemic has made changes to all aspects of life. Work must be done at home or somewhere outside the office. Although a virtual office is mostly done from one’s home, it can be done anywhere.
Yuliana Yuliana
doaj   +1 more source

Children and citizenship [PDF]

open access: yes, 2004
As an adjunct to the National Evaluation of On Track the Home Office Commissioned this qualitative research addressing the question of citizenship. The study included on children and young people from 7-15 years old, exploring their understandings of ...
Hine, Jean
core  

Adult Social Work and High Risk Domestic Violence Cases [PDF]

open access: yes, 2018
Summary This article focuses on adult social work’s response in England to high-risk domestic violence cases and the role of adult social workers in Multi-Agency Risk and Assessment Conferences. (MARACs).
Blood I.   +22 more
core   +1 more source

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