Results 31 to 40 of about 324,101 (218)

Locating home where discourses of gender and empire intersect: An analysis of selected excerpts from Lady Anne Barnard’s Cape diaries and journals

Contree, 2015
Lady Anne Barnard’s abundant textual legacy has received a great deal of academic attention with scholars scrutinising her letters, journals and diaries.
Jessica Murray
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Moran’s I Index and KKN-Based LISA

Jurnal Bina Praja
Stunting in toddlers is a significant nutritional issue that may negatively impact the quality of Indonesia’s future human resources. This study aims to analyze the spatial patterns of stunting prevalence in toddlers in Indonesia as a basis for ...
Yusharto Huntoyungo, Herdina Kuswari, Vice Admira Firnaherera, Halumma Zulfia Fitri, Alvian Imron Rosadi   +4 more
doaj   +1 more source

Homes for Canadians (II)

American, British and Canadian Studies Journal, 2021
According to Giorgio Agamben, the Greek term for ‘habitual dwelling place,’ or ‘habit,’ is ethos. The rise to prominence in the twentieth century of the modern idea of the suburb, or ‘suburbia,’ held open the door to the potential realization of the ...
HOWARD DAVID BRIAN
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Abstraktin ekspressionismin syntysijoilla

Tahiti, 2016
Tieteellinen ...
Marko Home
doaj  

Endoscopic stenting for malignant large-bowel obstruction as a management option for palliative patients in private medical practice: a case series and review of contemporary guidelines

Perioperative Medicine
Background. Malignant bowel obstruction is a frequent complication of colorectal cancer and is associated with high mortality, frequent stoma formation, and a marked deterioration in quality of life, especially in incurable patients.
Vitalii Rusakov, Svitlana Piriieva, Marko Chystiak, Dmytro Havrychenko, Ruslan Voloshyn, Serhii Semeniuk, Anzhelika Melnychenko, Kostiantyn Naumenko   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source