Results 41 to 50 of about 1,875,512 (268)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Challenging Hidden Oppression: Mothers Caring for Children with Disabilities

Critical Social Work, 2018
There is growing recognition that people with disabilities face oppression in a society which marginalizes those who are different; however, there is evidence that families living with disability also face exclusion, inadequate services and stigmatizing ...
Alice Home
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Homes for Canadians (II)

American, British and Canadian Studies Journal, 2021
According to Giorgio Agamben, the Greek term for ‘habitual dwelling place,’ or ‘habit,’ is ethos. The rise to prominence in the twentieth century of the modern idea of the suburb, or ‘suburbia,’ held open the door to the potential realization of the ...
HOWARD DAVID BRIAN
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Moran’s I Index and KKN-Based LISA

Jurnal Bina Praja
Stunting in toddlers is a significant nutritional issue that may negatively impact the quality of Indonesia’s future human resources. This study aims to analyze the spatial patterns of stunting prevalence in toddlers in Indonesia as a basis for ...
Yusharto Huntoyungo, Herdina Kuswari, Vice Admira Firnaherera, Halumma Zulfia Fitri, Alvian Imron Rosadi   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Endoscopic stenting for malignant large-bowel obstruction as a management option for palliative patients in private medical practice: a case series and review of contemporary guidelines

Perioperative Medicine
Background. Malignant bowel obstruction is a frequent complication of colorectal cancer and is associated with high mortality, frequent stoma formation, and a marked deterioration in quality of life, especially in incurable patients.
Vitalii Rusakov, Svitlana Piriieva, Marko Chystiak, Dmytro Havrychenko, Ruslan Voloshyn, Serhii Semeniuk, Anzhelika Melnychenko, Kostiantyn Naumenko   +7 more
doaj   +1 more source

Feeling at home in nursing homes [PDF]

Journal of Advanced Nursing, 2001
Feeling at home in nursing homes Aim. The purpose of this study was to examine determinants of feeling at home and in particular the privacy in nursing homes in The Netherlands. The first question was to what extent nursing homes differed in the degree residents feel at home and experience privacy.
A J, de Veer, A, Kerkstra
openaire   +2 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source