Results 51 to 60 of about 1,009,063 (266)

Advancing healthy ageing in Greece: the WHO ICOPE protocol within the JA PreventNCD framework

BMC Geriatrics
Introduction The World Health Organization’s Integrated Care for Older People (ICOPE) program is an evidence-based and user-friendly approach that supports healthy aging.
Theodoula Adamakidou, Alexandra Koreli, Neda Tavassoli, Chrysoula Tsiou   +3 more
doaj   +1 more source

Description of an advance care planning intervention in nursing homes: outcomes of the process evaluation

BMC Geriatrics, 2018
Background Advance Care Planning (ACP) is the repeated communication and decision-making process between the patient, family, and healthcare professionals.
Irene Aasmul, Bettina S. Husebo, Elisabeth Flo   +2 more
doaj   +1 more source

Feasibility of deploying peer coaches to mentor frontline home health aides and promote mobility among individuals recovering from a stroke: pilot test of a randomized controlled trial

Pilot and Feasibility Studies, 2022
Background Each year, approximately 100,000 individuals receive home health services after a stroke. Evidence has shown the benefits of home-based stroke rehabilitation, but little is known about resource-efficient ways to enhance its effectiveness, nor ...
Penny H. Feldman, Margaret V. McDonald, Nicole Onorato, Joel Stein, Olajide Williams   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Association of weight loss and decreased food intake with mortality in the oldest population: People in their 80s versus those aged ≥90 years

Archives of Gerontology and Geriatrics Plus
Objective: This study investigated the relationship between weight loss (WL), decreased food intake (DFI), and mortality among nursing home residents in their 80s and those aged ≥90 years.
Yuri Takada, Kasumi Ikuta, Sakiko Fukui
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Incidence and burden of hospitalizations for major respiratory infections among institutionalized adults followed by primary care residence units (UAR) in Madrid, Spain, September 2023–April 2025

Human Vaccines & Immunotherapeutics
Institutionalized older adults bear a disproportionate burden of severe respiratory infections, but population-based data from long-term care facilities remain limited.
Diego Martín-Caro Álvarez, Javier García Iglesias, Lara Alonso Bonete, María José del Olmo Rubio, Victoria García Martín, Paula Martín García, Ángel Gil de Miguel, Ruth Gil Prieto, María Alvargonzález Arrancudiaga, Eva Castillo Díaz, Ricardo Rodríguez Barrientos   +10 more
doaj   +1 more source