Results 131 to 140 of about 1,486,693 (344)

Study protocol of a mixed method pragmatic quasi-experimental trial to evaluate the day activity services targeted at older home care clients in Finland [PDF]

, 2022
Hanna Ristolainen, Leena Forma, Jemma Hawkins, Elisa Tiilikainen   +3 more
openalex   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Challenges in interdisciplinary collaboration in community health care – a focus group study and usefulness

Fysioterapeuten, 2014
Background: Due to health policy reform the community health care system faces new demands regarding interdisciplinary cooperation, active care and self-reliance. The aim of this study was to explore how physiotherapists and home care professionals look
Siri Moe, Torunn Hamran
doaj  

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

1210 PROVISION OF EYE CARE SERVICES AND INTERVENTIONS IN CARE HOMES - A NARRATIVE SYNTHESIS REVIEW [PDF]

, 2023
N. Ma, Sancy Low, Shukir S. Hasan, S Banna, S Patel, Tania Kalsi   +5 more
openalex   +1 more source

From Industrial Waste to Multistage Applications: Ultralight Lignin‐Based Aerogel with Situ Vertically Oriented Structure for Photothermal‐Assisted Pb2+ Adsorption in Wastewater and Reuse as Efficient Output and Stability Triboelectric Materials

Advanced Science, EarlyView.
Ultralight lignin‐based aerogel with situ vertically oriented structure for photothermally assisted adsorption of Pb2+, and then reused as lignin‐based triboelectric materials. Abstract In this work, the ultralight lignin‐based aerogel (GSPCAA) with situ vertically oriented structure is developed through a simple and green synthesis strategy for ...
Boyu Du, Yuxin Yang, Lingjing Huang, Yuxuan Xie, Xing Wang, Jinghui Zhou, Xingxiang Ji, Lupeng Shao   +7 more
wiley   +1 more source

Current perspectives on pharmacist home visits: do we keep reinventing the wheel?

Integrated Pharmacy Research and Practice, 2018
Priti S Flanagan,1,2 Andrea Barns1 1Pharmacy Community Programs, Lower Mainland Pharmacy Services, Langley, BC, Canada; 2Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada Abstract: The scope of clinical pharmacy ...
Flanagan PS, Barns A
doaj  

The meaning of ‘quality’ of homecare for older people: a scoping review

BMC Health Services Research
Background How quality of care in homecare for older people is understood is important, because it influences how quality in homecare is delivered, improved, regulated and measured.
Alex Hall, Vanessa Davey, Lisa McGarrigle, Jayne Astbury, Kimberly Lazo Green, Nisar Ahmed, Oleta Williams, Fiona Beyer, Barbara Hanratty, Debora Price   +9 more
doaj   +1 more source

Boosting Electrochemical Capacitive of Ultrathin Shower‐Pouf Birnessite‐Type MnO2 for Porous High‐Mass‐Loading Energy Storage Device

Advanced Science, EarlyView.
Ultrathin Shower‐pouf Birnessite‐type MnO2 (thickness: ~3 nm) has been fabricated via the specific adsorption of fluoride ions on the (001) crystal plane of birnessite. By constructing an electrically conductive network and optimizing electrode slurry concentration, the electrode mass loading can be substantially improved. These electrodes also exhibit
Shijin Zhu, Chenxin Zhang, Minghao Sun, Fangdie He, Yuxin Liu, Xinyi Guo, Mengwei Yao, Meng Zhao   +7 more
wiley   +1 more source