Results 131 to 140 of about 536,012 (299)

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Challenges in interdisciplinary collaboration in community health care – a focus group study and usefulness

Fysioterapeuten, 2014
Background: Due to health policy reform the community health care system faces new demands regarding interdisciplinary cooperation, active care and self-reliance. The aim of this study was to explore how physiotherapists and home care professionals look
Siri Moe, Torunn Hamran
doaj  

Medicalization of the private sphere: home care services in Manitoba

While aging in place is often idealized as a way to maintain comfort, autonomy, and emotional connection, for many informal caregivers, the home becomes a medicalized space shaped by public home care services. Drawing on 13 semi-structured interviews and
Kuryk, Kaitlyn
core  

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

T Cell‐Independent Role of PD‐L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD‐L1/BRCA1 Interaction Following AKI

Advanced Science, EarlyView.
PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang, Tao‐Tao Tang, Wei‐Jie Ni, Jin‐Xuan Wei, Liang‐Yun‐Zi Jiang, Qing Yin, Yi‐Lin Zhang, Zuo‐Lin Li, Yi Wen, Xin‐Lu Wang, Jun‐Yuan Shen, Xiao‐Jun Ouyang, Ming‐Zhu Zheng, Jian Xu, Xiaofei An, Lin‐Li Lv, Bi‐Cheng Liu, Bin Wang   +17 more
wiley   +1 more source

Patterns in use of aged care: 2002-03 to 2010-11 [PDF]

, 2014
In recent years greater emphasis has been placed on the provision of home-based support for older Australians. This report examines how this shift has affected the way that people use aged care programs, and investigates the initial take-up of care ...

core  

Multifaceted Roles of Tantalum in Promoting the Thermoelectric Performance of Mg3(Sb,Bi)2 Based Materials

Advanced Science, EarlyView.
A multifunctional tantalum incorporation strategy enables simultaneous tuning of carrier concentration, mitigation of grain‐boundary scattering, and enhanced phonon scattering in Mg3(Sb,Bi)2. These synergistic effects markedly improve carrier mobility and suppress lattice thermal conductivity, yielding both high material zT and high module conversion ...
Guangmeng You, Jingdan Lei, Kai Xu, Yuntian Fu, Xueke Gu, Chengxiao Peng, Zhen Wang, Jing Chen, Kunpeng Zhao, Chao Wang   +9 more
wiley   +1 more source

Structurally Complex Precipitates Enhance Strength‐Ductility Synergy in a Duplex Medium Entropy Alloy

Advanced Science, EarlyView.
Strong‐yet‐ductile precipitation‐hardening alloys require novel microstructural complexity of precipitates in particularly at cryogenic condition, to constantly impart strain hardening of hard‐and‐brittle precipitates. The present work creates innovative structurally complex precipitates assembled with dispersed nanocores and a chemical‐heterogeneity ...
Shaohua Gao, Yang Yang, Xiaoxuan Fan, Jinyu Zhang, Shuaiyang Liu, Jiao Li, Hui Wang, Wenli Song, Gang Liu, Jun Sun   +9 more
wiley   +1 more source

Current perspectives on pharmacist home visits: do we keep reinventing the wheel?

Integrated Pharmacy Research and Practice, 2018
Priti S Flanagan,1,2 Andrea Barns1 1Pharmacy Community Programs, Lower Mainland Pharmacy Services, Langley, BC, Canada; 2Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada Abstract: The scope of clinical pharmacy ...
Flanagan PS, Barns A
doaj  

The meaning of ‘quality’ of homecare for older people: a scoping review

BMC Health Services Research
Background How quality of care in homecare for older people is understood is important, because it influences how quality in homecare is delivered, improved, regulated and measured.
Alex Hall, Vanessa Davey, Lisa McGarrigle, Jayne Astbury, Kimberly Lazo Green, Nisar Ahmed, Oleta Williams, Fiona Beyer, Barbara Hanratty, Debora Price   +9 more
doaj   +1 more source