Results 91 to 100 of about 43,032 (254)

Applying Change Models and Methods During a Period of Vast Digital Transformation: A Systematic Review of Practice in Healthcare

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction Reflection and learning about the use of virtual care in healthcare delivery has become a central goal for health systems internationally. Insights drawn in the aftermath of the COVID‐19 pandemic have led to vast changes to embed virtual care in health care delivery. This study explored the methodologies used to manage change that
Rebecca McDonnell, Ashfaq Chauhan, Corey Adams, Alexander Cardenas, Michelle Moscova, Ramya Walsan, Maryam Sina, Alice Munro, Elizabeth Manias, Rebecca Mitchell, Anthony Gust, Sabe Sabesan, Reema Harrison   +12 more
wiley   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Otologic Surgery Risk Prediction: Risk Analysis Index‐Administrative Versus Modified Frailty Index‐5

The Laryngoscope, EarlyView.
In a national cohort of 2862 patients undergoing otologic surgery, the risk analysis index‐administrative (RAI‐A) outperformed the modified frailty index‐5 (mFI‐5) in predicting key 30‐day postoperative outcomes, including mortality, complications, surgical site infection, extended length of stay, and nonhome discharge.
Akshay Warrier, Nicole Kim, Ryan Bartholomew, Liliya Benchetrit, Daniel J. Lee   +4 more
wiley   +1 more source

Risk Analysis Index Versus mFI‐5 for Predicting Outcomes After Uvulopalatopharyngoplasty

The Laryngoscope, EarlyView.
This retrospective database study of 2129 adults undergoing uvulopalatopharyngoplasty compared the risk analysis index (RAI) with the modified 5‐item frailty index (mFI‐5) for predicting 30‐day postoperative outcomes and found that frailty was associated with worse morbidity, prolonged hospitalization, non‐home discharge, and mortality.
Akshay Warrier, Ariana Shaari, Aman M. Patel, Christian Bowers, Kenneth Yan   +4 more
wiley   +1 more source

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake, Tatsuya Hirata, Shunsuke Nomura, Kenji Konishi, Kazunari Yoneda, Shin‐ichi Sakasegawa, Haruhiko Sakuraba   +6 more
wiley   +1 more source

Redox‐responsive dual‐drug nanomedicine integrating cisplatin and trypsin for synergistic reversal of tumor chemoresistance

Smart Molecules, EarlyView.
This study presents a novel glutathione‐activatable prodrug nanomedicine (cRGD‐PEG‐PGlu‐NP (ssTrypsin & CDDP)) that co‐encapsulates cisplatin and a masked protease to combat cisplatin resistance. The dual‐drug system selectively targets resistant tumor cells, enhancing the efficacy of cisplatin while minimizing systemic toxicity.
Xiaolan Yin, Qi Wang, Ming Zhang, Cheng Zhang, Qixian Chen, Haidong Li, Yan Zhao, Yue Wang, Jingyun Wang, Liuwei Zhang, Hongyan Cui   +10 more
wiley   +1 more source

Amyloid‐Like Protein Assembly‐Driven Functional Materials for Enabling the Sustainable Development of Light Industry

SusMat, EarlyView.
This article covers the basic theory and regulation strategies of amyloid‐like protein assembly, reviews the research progress of amyloid‐like protein assembly‐driven functional materials in light industry fields such as food, packaging, textiles, and biocatalysis, analyzes their sustainable advantages and challenges in these applications, and offers ...
Ruirui Liu, Zuying Chen, Jian Zhao, Fengjian Wang, Changli Zeng, Peng Yang   +5 more
wiley   +1 more source

Longitudinal changes in peritoneal solute transport rate and the impact of lower glucose degradation product glucose dialysates

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 471-478, June 2025.
Abstract Introduction Peritoneal solute transfer rates (PSTR) are reported to increase with time. Changes in PSTR were reviewed in long‐term peritoneal dialysis (PD) patients to determine whether lower glucose degradation products (low GDP) dialysates prevented an increase in PSTR. Methods PSTR was determined with a 4‐h peritoneal equilibrium test with
Andrew Davenport
wiley   +1 more source

Clinical Vignette: Piperacillin/tazobactam‐associated myoclonic status epilepticus in a patient with end‐stage renal failure on hemodialysis

Epileptic Disorders, EarlyView.
O. M. Malanga, G. Giovannelli, G. Pastorelli, S. Fittante, A. Poggesi, E. Rosati   +5 more
wiley   +1 more source

Text mining for case report articles on “peritoneal dialysis” from PubMed database

Therapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 459-470, June 2025.
Abstract Introduction The number of published medical articles on peritoneal dialysis (PD) has been increasing, and efficiently selecting information from numerous articles can be difficult. In this study, we examined whether artificial intelligence (AI) text mining can be a good support for efficiently collecting PD information.
Kazuhiko Fukushima, Kenji Tsuji, Hiroyuki Nakanoh, Naruhiko Uchida, Soichiro Haraguchi, Shinji Kitamura, Jun Wada   +6 more
wiley   +1 more source