Results 161 to 170 of about 43,032 (254)
Targeted Delivery of mRNA to the Heart via Extracellular Vesicles or Lipid Nanoparticles
ABSTRACT Efficient and specific delivery of mRNA to target tissues is critical for maximising therapeutic benefits while minimising off‐target effects and systemic toxicity. Systemic administration of mRNA using lipid nanoparticles (LNPs) or extracellular vesicles (EVs) typically leads to predominant accumulation in the liver.
Muhammad Nawaz +13 more
wiley +1 more source
Transferring From Peritoneal Dialysis to Home or In-Center Hemodialysis: A Cohort Study of an Integrated Home Dialysis Model. [PDF]
Mahmoud J +4 more
europepmc +1 more source
ABSTRACT Introduction Foot‐related conditions are a leading cause of all hospitalisations and amputations worldwide. Half of these foot‐related hospitalisations are in people without diabetes. Yet, few studies seem to have explored risk factors for foot‐related hospitalisations in populations with or without diabetes. This study aimed to systematically
Sucharitha R. Weerasuriya +5 more
wiley +1 more source
The way home: a scoping review of public health interventions to increase the utilization of home dialysis in chronic kidney disease patients. [PDF]
Yongphiphatwong N +9 more
europepmc +1 more source
Abstract Genomic sequencing (GS) for patients and families with rare disease creates the opportunity for precise diagnosis as well as the option to learn about medically actionable secondary findings (SF). Debate persists internationally on how to manage the analysis and disclosure of SF, especially in settings where service delivery models for GS are ...
Abigail Hansen +36 more
wiley +1 more source
Home Dialysis in Patients with Cardiovascular Diseases. [PDF]
Reaves AC +3 more
europepmc +1 more source
ABSTRACT Introduction Safe outpatient delivery of B‐cell maturation antigen–targeting bispecific antibodies (BCMA‐BsAbs) in multiple myeloma (MM) is challenging, particularly during step‐up dosing (SUD). Standardized guidance for European community practice is limited.
María‐Victoria Mateos +10 more
wiley +1 more source
HA1@diABZI–HMGB1 serves as a synergistic immunomodulator for dismantling the immunosuppressive microenvironment of esophageal squamous cell carcinoma (ESCC), it integrates ESCC‐targeted recognition, HMGB1‐mediated macrophage–tumor cell bridging, and diABZI‐driven STING activation.
Chaofan Huang +10 more
wiley +1 more source
Corrigendum to "Pregnancies in Women With Kidney Failure on Home Dialysis in the United States" [<i>Kidney International Reports</i> Volume 9, Issue 4, April 2024, Pages 907-918]. [PDF]
Shah S +6 more
europepmc +1 more source

