Results 71 to 80 of about 1,756,094 (323)

Serviços de atenção ao idoso e estratégias de cuidado domiciliares e institucionais

Revista Brasileira de Geriatria e Gerontologia
INTRODUÇÃO: As redes de atenção à saúde são fundamentais para assistir a população idosa em seus diversos aspectos. A assistência domiciliar, o Programa Acompanhante de Idosos da Secretaria Municipal da Saúde da cidade de São Paulo e as instituições de ...
Fernanda Pretti Chalet Ferreira, Luciana Orui Bansi, Sérgio Márcio Pacheco Paschoal   +2 more
doaj   +1 more source

Educational aspirations in inner city schools [PDF]

, 2008
The research aimed to assess the nature and level of pupils’ educational aspirations and to elucidate the factors that influence these aspirations. A sample of five inner city comprehensive secondary schools were selected by their Local Authority because
Addams H., Alloway N., Appadurai A., Blair T., Bourdieu P., Fenton S., Joe Winston, Jowell T., Khoo S.T., McLeod J., Ogbu J., Payne J., Penn R., Steve Strand, Strand S., Strand S., Wentzel K.R.   +16 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Pollution fears are misplaced while toxins thrive indoors air filters can reduce heart and lung disease, a new study reveals, because air quality is so poor inside modern houses [PDF]

, 2008
Following the smoking ban, advocates of clean air might have believed that the battle was largely won. However, worrying new research highlights the pernicious effects of other life-threatening pollutants.
Duffy, Marisa, Howieson, Stirling
core  

Is telomere length socially patterned? Evidence from the West of Scotland Twenty-07 study [PDF]

, 2012
Lower socioeconomic status (SES) is strongly associated with an increased risk of morbidity and premature mortality, but it is not known if the same is true for telomere length, a marker often used to assess biological ageing. The West of Scotland Twenty-
A Aviv, A Aviv, A Benetos, A Steptoe, Alan McIntyre, AT Geronimus, AV Diez Roux, BM Unryn, CG Parks, CM Martin-Ruiz, D Janicki-Deverts, D Kuh, E Fernandez-Egea, ES Epel, F Maxwell, G Aubert, G. David Batty, GD Batty, Geoff Der, H Sies, J Adams, J Carrero, J Woo, JM Adams, John C. S. Breitner, K Lorimer, K Nordfjall, K Yaffe, KA Mather, KA Mather, L Kananen, LA Deroo, LF Cherkas, LF Cherkas, LF Hou, Liane M. McGlynn, M Benzeval, M Lee, M Walsh DT, MA Blasco, MG Marmot, Michael J. Green, Michaela Benzeval, NE Adler, NE Adler, P McLoone, Paul G. Shiels, PG Shiels, PG Shiels, PG Surtees, R Chan, RA Risques, RM Cawthon, RM Cawthon, S Macintyre, S Seaman, SE Harris, SE Harris, SM Lynch, T de Lange, T De Meyer, T von Zglinicki, T von Zglinicki, Tony Robertson, TS Nawrot, V Carstairs, W Chen, YL Zheng   +67 more
core   +6 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Why has home ownership fallen among the young? [PDF]

We document that home ownership of households with 'heads' aged 25-44 years fell substantially between 1980 and 2000 and recovered only partially during the 2001-2005 housing boom. The 1980-2000 decline in young home ownership occurred as improvements in
Jonas D. M. Fisher, Martin Gervais
core   +6 more sources

Health profile of older adults assisted by the Elderly Caregiver Program of Health Care Network of the City of São Paulo

Einstein (São Paulo)
Objective To assess the health profile of community-dwelling older adults, according to sex, assisted by the Elderly Caregiver Program of the City of São Paulo.
Suzana Carvalho Vaz de Andrade, Rosa Maria Bruno Marcucci, Lilian de Fátima Costa Faria, Sérgio Márcio Pacheco Paschoal, Flávio Rebustini, Ruth Caldeira de Melo   +5 more
doaj   +2 more sources

Construction of a Hospice Service Model for Elderly Care Institutions in China [PDF]

Zhongguo quanke yixue
Background With the acceleration of the aging process in society, the demand for hospice services is increasing. The development of hospice care in China started relatively late, and relevant institutional construction standards and management norms are ...
WANG Huaping, ZHU Huajie, ZHU Chunman, PAN Danhong
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source