Results 101 to 110 of about 257,172 (346)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Control of hyperglycaemia in paediatric intensive care (CHiP): study protocol. [PDF]

, 2010
BACKGROUND: There is increasing evidence that tight blood glucose (BG) control improves outcomes in critically ill adults. Children show similar hyperglycaemic responses to surgery or critical illness.
A Ceriello, A Ceriello, A Ceriello, A Chiaretti, A Rovlias, A Russo, A Russo, AA Ferrando, AA Ferrando, Allan Goldman, Ann Truesdale, AP Furnary, AP Furnary, B Halverson-Steele, CK Rayner, Claire Snowdon, D Ardigo, D Ardigo, D Ardigo, D Field, DA Schoenfeld, DC Angus, DC Angus, Deborah Percy, Diana Elbourne, Duncan Macrae, Elizabeth Allen, EV Faustino, G Paret, G Van den Berghe, G Van den Berghe, Helen Betts, J Lacroix, JL Haybittle, JM Hoxworth, John Pappachan, K Esposito, K Katsura, K Malmberg, K Malmberg, Kevin Morris, KJ Jenkins, LM McManus, M Cornblath, MAQ Curley, Margrid Schindler, Mark Peters, MF Oliver, Michael Broadhead, MM Gearhart, NJ Hall, P Lange, PA Li, Paul Baines, Peter-Marc Fortune, R Peto, RE Anderson, RG Branco, Richard Grieve, Robert Tasker, Roger Parslow, S Leteurtre, S Yendamuri, SE Capes, SE Capes, Simon Nadel, Tara Quick, The Acute Respiratory Distress Syndrome Network, TM Vriesendorp, TN Pham, UN Das, UN Das, UN Das, V Srinivasan, WA Pulsinelli, WD Dietrich, Zdenek Slavik   +76 more
core   +5 more sources

Cost comparison analysis of continuous versus intermittent antimicrobial therapy infusions in inpatient and outpatient care: real-world data from Finland

BMJ Open
Objective This study compared the costs and nursing time associated with the delivery of continuous infusion of antibiotics via elastomeric infusion pumps (EIP) versus conventional intermittent infusion (CII) across different care pathways.Design ...
Julian Shepelev, Terhi Rahkonen, Ville Lehtinen, Tuukka Hakkarainen, Mari Lahelma, Trine Gram, Eija Heikkila   +6 more
doaj   +1 more source

Intestinal transplantation in composite visceral grafts or alone [PDF]

, 1992
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match).
Abu-Elmagd, K, Busuttil, RW, Casavilla, A, Demetris, AJ, Fung, JJ, Nakamura, K, Nour, BM, Rapaport, FT, Reyes, J, Selby, R, Shaw, BW, Starzl, TE, Thompson, JC, Todo, S, Tzakis, AG, Van Thiel, DH, Vasconez, LO, Wright, H   +17 more
core   +1 more source

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

Advanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham, Juan M. Rojas Cabrera, Youngjong Kwak, Lydia Hong, Andre Chambers, Athavan Nadarajah, Sorel E. De Leon, Young Jun Jung, Negin Jalilinejad, Charles Blaha, Dong Pyo Jang, Yoonbae Oh, Kendall Lee, Alastair Stacey, Shaun L. Cloherty, Michael R. Ibbotson, David J. Garrett, Steven Prawer, Hojin Shin, Wei Tong   +19 more
wiley   +1 more source

Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999. [PDF]

, 2004
Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo.
Borchert, M, Colebunders, R, Kinuani, L, Libande, M, Mustin, J P, Muyembe-Tamfum, J J, Olinda, L A, Pirard, P, Sleurs, H, Tshioko, F, Tshomba, A   +10 more
core   +2 more sources

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Patient Preferences for Faster Home-Based Subcutaneous Immunoglobulin Infusion Therapy and the Effect on Adverse Events

Patient Preference and Adherence
Brent Rutland,1,* Carleton Southworth,2,* Jasmin Bosshard1 1Medical Affairs, KORU Medical Systems Inc., Mahwah, NJ, USA; 2American Research Partners LLC, South Bend, IN, USA*These authors contributed equally to this workCorrespondence: Jasmin
Rutland B, Southworth C, Bosshard J
doaj