Results 141 to 150 of about 11,383,391 (296)

COVID-19 and bilingual children's home language environment: Digital media, socioeconomic status, and language status. [PDF]

Front Psychol, 2023
Sun H, Tan J, Chen W.
europepmc   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

THE ROLE OF HOME LANGUAGE AND HOME LANGUAGE ENVІRONMENT ІN THE EDUCATІON AND UPBRІNGІNG OF YOUTH

Visnyk Taras Shevchenko National University of Kyiv. Pedagogy
Background. The artіcle studіes the pressіng іssue of the іmportance of the Ukraіnіan language and home language envіronment іn educatіng the young generatіon. Іt hіghlіghts changes іn the economіc, polіtіcal, cultural, and educatіonal lіfe of socіety, as well as the challenges of the polіtіcal sіtuatіon іn the country, whіch have led some іndіvіduals ...
openaire   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Home language and literacy environment and its relationship to socioeconomic status and white matter structure in infancy. [PDF]

Brain Struct Funct, 2022
Turesky TK, Sanfilippo J, Zuk J, Ahtam B, Gagoski B, Lee A, Garrisi K, Dunstan J, Carruthers C, Vanderauwera J, Yu X, Gaab N.   +11 more
europepmc   +1 more source

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

The Bilingual Home Language Boost Through the Lens of the COVID-19 Pandemic. [PDF]

Front Psychol, 2021
Sheng L, Wang D, Walsh C, Heisler L, Li X, Su PL.   +5 more
europepmc   +1 more source

High‐Brightness and Ultra‐Long‐Lifetime Spin Quantum Dot Light‐Emitting Diodes Enabled by Efficient Injection of Spin‐Polarized Holes Through a Hybrid Hole Transport Layer

Advanced Science, EarlyView.
This work employs a hybrid hole transport layer to enhance hole transport efficiency, resulting in improved performance for the final device. It achieves an external quantum efficiency of 6.68%, a circularly polarized electroluminescence asymmetry factor of 0.026, and a high luminance of 14,370 cd/cm2, representing the highest luminance reported to ...
Fengqi Qiu, Hechun Zhang, Wenbo Liu, Guiming Zhong, Fumin Lu, Yuqi Wang, Fujin Ai, Kai Wang, Dan Wu   +8 more
wiley   +1 more source

Multiferroic Quantum Criticality in a Proper Ferroelectric Quasi‐one‐dimensional Ising Antiferromagnet

Advanced Science, EarlyView.
Sr1−xBaxCo2V2O8 is established as a magnetic‐ion‐based proper displacive ferroelectric whose transition is continuously suppressed by Ba substitution to a ferroelectric quantum critical point. In the resulting quantum paraelectric regime, a transverse magnetic field induces magnetic quantum criticality, realizing multiferroic quantum criticality and ...
Takayuki Nagai, Peisen Yu, Akitoshi Nakano, Tsuyoshi Kimura   +3 more
wiley   +1 more source