Results 51 to 60 of about 947,286 (298)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
An Australian abroad : the secret life of the brushtail possum (Trichosurus vulpecula) : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Manawatu, New Zealand [PDF]
, 2016 The “superspreader” hypothesis relates disease transmission to social contacts and assumes transmission is driven by the frequency, type and distribution of contacts among infected and susceptible individuals.
Richardson, Kyle Stephen
core
Female home range size is regulated by resource distribution and intraspecific competition: a long-term field study [PDF]
, 2010 The size of an individual’s home range is an important feature, influencing reproduction and survival, but it can vary considerably among both populations and individuals.
Bleeker, M +9 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Endangered Species Research, 2014 Geographic variation in the levels of persistent organic pollutants (POPs) was assessed in the serum of Hawaiian monk seals Monachus schauinslandi from the main Hawaiian Islands. Twenty seals were outfitted with tracking devices to map their home ranges,
J Lopez +3 more
doaj +1 more source
Factors Affecting Home Ranges of Red Foxes in Ikh Nart Nature Reserve, Mongolia [PDF]
Mongolian Journal of Biological Sciences, 2012 Changes in red fox home range size in relation to environmental and intrinsic factors were studied using radio-telemetry during 2006–2008 in Ikh Nart Nature Reserve, southeastern Mongolia. We captured a total of 12 red
Tserendorj Munkhzul +4 more
doaj +1 more source
Space use by foragers consuming renewable resources [PDF]
, 2014 We study a simple model of a forager as a walk that modifies a relaxing substrate. Within it simplicity, this provides an insight on a number of relevant and non-intuitive facts.
Abramson, Guillermo +3 more
core +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A new methodology for computing birds’ 3D home ranges
Avian Research, 2018 Background So far, studies of avian space use are mostly realized in 2D, with the vertical dimension ignored. We propose here a new, relatively simple and computationally reasonable method for the estimation of volumetric (i.e.
Alessandro Ferrarini +4 more
doaj +1 more source
BMC Ecology, 2020 Background Competition within and between social groups determines access to resources and can be inferred from space use parameters that reflect depletion of food resources and competitive abilities of groups.
Nicole Seiler, Martha M. Robbins
doaj +1 more source