Results 51 to 60 of about 13,729 (150)

Safety and tolerability of pirfenidone in asbestosis: a prospective multicenter study

open access: yesRespiratory Research, 2022
Background Pirfenidone slows down disease progression in idiopathic pulmonary fibrosis (IPF). Recent studies suggest a treatment effect in progressive pulmonary fibrosis other than IPF.
Jelle R. Miedema   +7 more
doaj   +1 more source

‘What’ and ‘How’ to Measure in Allergy and Clinical Immunology: A Systematic Review of Core Outcome Sets and Outcome Harmonisation Processes

open access: yesClinical &Experimental Allergy, EarlyView.
This systematic review maps core outcome sets and harmonisation efforts in allergy and clinical immunology. Despite shared priorities such as quality of life and symptoms, substantial gaps and methodological inconsistencies remain, underscoring the need for broader coverage and standardised outcome measurement to improve comparability and clinical ...
Anastasia Demidova   +45 more
wiley   +1 more source

Immune checkpoint inhibitor cardiomyotoxicity: a case series of five patients and development of a clinical management algorithm

open access: yesInternal Medicine Journal, EarlyView.
Abstract Immune checkpoint inhibitor (ICI) therapies have revolutionised the management of a range of malignancies. However, the syndrome of ICI induced cardiomyotoxicity, also reported as triple “M” syndrome (myasthenia gravis, myositis and myocarditis) is an unfortunate severe consequence in up to 1%–2% of patients receiving ICI, with an associated ...
S. Z. Xie   +14 more
wiley   +1 more source

Proactive Electronic Visits for Smoking Cessation and Chronic Obstructive Pulmonary Disease Screening in Primary Care: Randomized Controlled Trial of Feasibility, Acceptability, and Efficacy

open access: yesJournal of Medical Internet Research, 2022
BackgroundMost smokers with chronic obstructive pulmonary disease (COPD) have not yet been diagnosed, a statistic that has remained unchanged for over two decades.
Jennifer Dahne   +10 more
doaj   +1 more source

A multi‐centre retrospective review of the bronchoscopic management of upper tracheal stenosis: An Australian perspective

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Upper tracheal stenosis (UTS) is a rare process with multiple causes and variable approaches to treatment. Australian data on management patterns are lacking and patient resources reflecting local practices are scarce. Aims To describe the management strategies of UTS over 12 years among three teaching hospitals in New South Wales ...
Nathan Harb   +6 more
wiley   +1 more source

COPD Management in Primary Care: Underutilisation of Nursing Consultations

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Objective To describe the clinical profile, comorbidity burden, follow‐up and healthcare utilisation in patients labelled as having Chronic Obstructive Pulmonary Disease (COPD) in Primary Care (PC) nursing consultations. Design Real‐world data COPD, retrospective, observational study using routinely collected data in electronic health records (
Marc Vila   +6 more
wiley   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor   +4 more
wiley   +1 more source

Monitoring respiratory function with telemedicine devices in asthmatic children

open access: yesFrontiers in Medicine
IntroductionPediatric asthma requires continuous monitoring, traditionally reliant on in-person assessments. Home-based telespirometry offers a promising approach, enabling regular lung function testing, early exacerbation detection, and improved disease
Katalin Kapus   +5 more
doaj   +1 more source

Respiratory safety of lemborexant in adult and elderly subjects with moderate‐to‐severe chronic obstructive pulmonary disease

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Lemborexant 10 mg, a dual orexin‐receptor antagonist (DORA), did not elicit respiratory depressant effects, as measured by peripheral oxygen saturation (SpO2) or apnea–hypopnea index (AHI), in subjects with moderate‐to‐severe chronic obstructive pulmonary disease (COPD).
Jocelyn Y. Cheng   +3 more
wiley   +1 more source

Respiratory muscle endurance training among patients with chronic diseases: A systematic review of available evidence

open access: yesExperimental Physiology, EarlyView.
Abstract This systematic review summarizes the available evidence on respiratory muscle endurance training involving voluntary isocapnic hyperpnoea among patients with chronic diseases. It includes both randomized and non‐randomized controlled trials implementing this exercise training modality performed either alone or in combination with other ...
Hélène Laurent   +3 more
wiley   +1 more source

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