Results 231 to 240 of about 34,206 (311)

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

open access: yesAdvanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim   +4 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

open access: yesAdvanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu   +14 more
wiley   +1 more source

Comparison of methods for isolation of extracellular vesicles from bronchoalveolar lavage fluid. [PDF]

open access: yesExtracell Vesicles Circ Nucl Acids
Fraser ME   +10 more
europepmc   +1 more source

Racial and Ethnic Disparities in the Management and Outcomes of Acute Myocardial Infarction Complicated by Ventricular Arrhythmias. [PDF]

open access: yesJ Clin Med
Randhawa M   +10 more
europepmc   +1 more source

The tyrosine phosphatase STEP is a developmental suppressor of synaptogenesis. [PDF]

open access: yesProc Natl Acad Sci U S A
Pires JP   +7 more
europepmc   +1 more source

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