Results 51 to 60 of about 9,189 (259)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
TECHNO-ECONOMIC ANALYSIS OF AN OFF-GRID HYBRID ENERGY SYSTEM WITH HOMER PRO
ICONTECH INTERNATIONAL JOURNAL, 2021 The decrease in fossil-based energy sources and increasing environmental problems increase the tendency to renewable energy sources day by day. The potential of renewable energy sources differs according to the region where the energy will be produced.
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Optimization of a Hybrid Off-Grid Solar PV—Hydro Power Systems for Rural Electrification in Cameroon
Journal of Electrical and Computer EngineeringThe use of decentralized renewable energy systems will continue to play a significant role in electricity generation especially in developing countries where grid expansion to most remote areas is uneconomical.
Chu Donatus Iweh +2 more
doaj +1 more source
Hybrid renewable energy system design for a green port using HOMER Pro: A techno-economic assessment
International Journal of Renewable Energy DevelopmentMaritime plays an important role in the national economy since a large number of goods in the world are transported by sea, although maritime transport is found to generate the largest greenhouse gas emission among transportation means.
Gia Huy Dinh +6 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Energies, 2023 One of the biggest issues impeding a country’s progress is the lack of power. To overcome this issue, hybrid renewable energy systems (HRES) play an important role. Due to rising consumption and diminishing resources globally, sustainability has recently
Md. Rasel Ahmed +4 more
doaj +1 more source
Design of hybrid power system for COMSATS University Islamabad using homer pro software
International Journal of Engineering, Science and Technology, 2023 More than a billion people do not have access o electricity, so it is important to find ways to generate power close to where they live. Hybrid energy systems can be made and used to generate electricity for homes and businesses that are not connected to national or regional power grids.
Rashid, Amir +2 more
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source