Results 181 to 190 of about 363,464 (283)

Ketogenic metabolic therapy as a candidate adjunct for CBTp delivery in schizophrenia spectrum disorders. [PDF]

Front Psychol
Laurent N.
europepmc   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Prospective study on the impact of parental anxiety on academic performance in children with attention deficit. [PDF]

World J Psychiatry
Jin Y, Xiao YS, Zhou P.
europepmc   +1 more source

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

Advanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang, Hui Yang, Baoyuan Zhang, Yongsu Ma, Kuangen Zhang, Peng Wang, Jiapeng Yang, Zaiqi Wang, Rong Liu, Xiaodong Tian, Ning Zhang, Yinmo Yang   +11 more
wiley   +1 more source

Charge Your Brainzzz: the systematic development of a whole systems action program promoting sleep health in adolescents. [PDF]

BMC Public Health
Heemskerk DM, Busch V, Piotrowski JT, Renders CM, van Stralen MM.   +4 more
europepmc   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Effect of perceived school environment on adolescent depression: the moderating role of intergenerational interactions. [PDF]

BMC Psychol
Cui J, Li X, Yao S.
europepmc   +1 more source

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

Advanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li, Guorui Zhang, Xinyue Wang, Zhongyu Liu, Ling Yang, Yuhan Bao, Min Wei, Yonglin Chen, Yanfei Ma, Wenbo Sheng, Bo Yu, Bin Li   +11 more
wiley   +1 more source

Tracking Secondary School Students: A Qualitative Investigation of an Online Student Monitoring System With Parent Portal. [PDF]

J Sch Health
Meuleman EM, Koning IM, Heemskerk DM, Busch V, van Stralen MM.   +4 more
europepmc   +1 more source

Homeworking [PDF]

, 1987
Sheila Allen, Carol Wolkowitz
openaire   +1 more source