Results 1 to 10 of about 49,402 (159)
Natural killer cell homing and trafficking in tissues and tumors: from biology to application
Signal Transduction and Targeted Therapy, 2022 Natural killer (NK) cells, a subgroup of innate lymphoid cells, act as the first line of defense against cancer. Although some evidence shows that NK cells can develop in secondary lymphoid tissues, NK cells develop mainly in the bone marrow (BM) and ...
Guang he Ran +6 more
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Mesenchymal Stromal Cell Homing: Mechanisms and Strategies for Improvement
iScience, 2019 Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic potential in regenerative medicine, owing to their ability to home damaged tissue and serve as a reservoir of growth factors and regenerative molecules.
Mujib Ullah +2 more
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The Bone Marrow Is Akin to Skin: HCELL and the Biology of Hematopoietic Stem Cell Homing [PDF]
Journal of Investigative Dermatology, 2004 The recent findings that adult stem cells are capable of generating new blood vessels and parenchymal cells within tissues they have colonized has raised immense optimism that these cells may provide functional recovery of damaged organs. The use of adult stem cells for regenerative therapy poses the challenging task of getting these cells into the ...
Robert Sackstein
exaly +4 more sources
Olfaction Contributes to Pelagic Navigation in a Coastal Shark. [PDF]
, 2016 How animals navigate the constantly moving and visually uniform pelagic realm, often along straight paths between distant sites, is an enduring mystery. The mechanisms enabling pelagic navigation in cartilaginous fishes are particularly understudied.
Chai, Fei +4 more
core +18 more sources
Cell Chemical Biology: Home of Exciting Chemical Biology [PDF]
Cell Chemical Biology, 2016 Table of Content Wish List“An Atomic Resolution Map of a Working Cell” (Bridget Carragher)“A Universal Method for Compound Target Identification” (James K. Chen)“A Lego Kit of Biosynthetic Modules for Secondary Metabolite Production” (James K. Chen)“Quantitative Sequencing of Carbohydrate Modifications on Proteins” (James K.
Kostic, M +4 more
openaire +3 more sources
Pharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansion. [PDF]
PLoS ONE, 2012 BACKGROUND: Expansion of hematopoietic stem/progenitor cells (HSPCs) is a well-known strategy employed to facilitate the transplantation outcome. We have previously shown that the prevention of apoptosis by the inhibition of cysteine proteases, caspase ...
V M Sangeetha +3 more
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Computational cell biology at the home of the helix [PDF]
EMBO reports, 2010 The Computational Cell Biology Conference, held jointly by the Cold Spring Harbor Laboratory and the Wellcome Trust, was convened in the grand surroundings of Hinxton Hall near Cambridge, UK. The high quality of the research presented at the meeting confirmed that the field of computational cell biology is maturing rapidly, which mirrors the ...
Jonathan J, Ward, Francois J, Nédélec
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Homing in on the Sweet Side of Immune Checkpoint Biology [PDF]
Immunity, 2016 P-selectin glycoprotein ligand-1 (PSGL-1) and its glycostructural determinants facilitate responses to infection and cancer by promoting immune effector-cell trafficking into inflamed tissue. In this issue of Immunity, Tinoco et al. (2016) report homing-independent functions of PSGL-1 in immune checkpoint regulation and T cell effector activity, in ...
Steven R, Barthel, Tobias, Schatton
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Designer self-assembling peptide nanofiber scaffolds for adult mouse neural stem cell 3-dimensional cultures. [PDF]
PLoS ONE, 2006 Biomedical researchers have become increasingly aware of the limitations of conventional 2-dimensional tissue cell culture systems, including coated Petri dishes, multi-well plates and slides, to fully address many critical issues in cell biology, cancer
Fabrizio Gelain +3 more
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Current Understanding of Extracellular Vesicle Homing/Tropism
Zoonoses, 2022 Extracellular vesicles (EVs) are membrane-enclosed packets that are released from cells and subsequently transfer bioactive molecules between cells without directly contacting the target cells.
Mariola J. Edelmann, Peter E. Kima
doaj +1 more source